Results 121 to 130 of about 231,010 (425)

Facet-sparing lumbar decompression with a minimally invasive flexible MicroBlade Shaver® versus traditional decompression: quantitative radiographic assessment. [PDF]

, 2012
BackgroundLaminectomy/laminotomy and foraminotomy are well established surgical techniques for treatment of symptomatic lumbar spinal stenosis. However, these procedures have significant limitations, including limited access to lateral and foraminal ...
Berven, Sigurd, Block, Jon E, Lauryssen, Carl, Miller, Larry E, Mimran, Ronnie, Sheinberg, Michael, Summa, Christopher   +6 more
core   +2 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

LC-GAN: Image-to-image Translation Based on Generative Adversarial Network for Endoscopic Images [PDF]

arXiv, 2020
Intelligent vision is appealing in computer-assisted and robotic surgeries. Vision-based analysis with deep learning usually requires large labeled datasets, but manual data labeling is expensive and time-consuming in medical problems. We investigate a novel cross-domain strategy to reduce the need for manual data labeling by proposing an image-to ...
arxiv  

A VARIATION IN THE COURSE OF THE HUMAN VERTEBRAL ARTERY: ANATOMICAL AND CLINICAL SIGNIFICANCE

Acta Medica Iranica, 1999
The macroscopic study of 31 adult cadavers proved a variation to Matula and Lang's study. In 2 cases (6.4%) a prevertebral segment ran up to Cy in one of which (3.2%) the middle cervical ganglion was pierced.
M. Akbari, H. Marzban M. Toback   +1 more
doaj  

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Autonomous Driving in the Lung using Deep Learning for Localization [PDF]

arXiv, 2019
Lung cancer is the leading cause of cancer-related death worldwide, and early diagnosis is critical to improving patient outcomes. To diagnose cancer, a highly trained pulmonologist must navigate a flexible bronchoscope deep into the branched structure of the lung for biopsy.
arxiv  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Quantifying Cross-scatter Contamination in Biplane Fluoroscopy Motion Analysis Systems [PDF]

, 2015
Biplane fluoroscopy is used for dynamic in vivo three-dimensional motion analysis of various joints of the body. Cross-scatter between the two fluoroscopy systems may limit tracking accuracy. This study measured the magnitude and effects of cross-scatter
Cross, Janelle A., Gilat-Schmidt, Taly, McHenry, Ben   +2 more
core   +2 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

The use of cadaver tissues in transplantation

Transplantation, 1964
IN the short span of thirteen years human-kidney homotransplantation has progressed from developmental uncertainty to a therapeutic endeavor that has rehabilitated many patients in terminal renal failure, both in this country and abroad. Contrary to many apprehensions, the use of drugs to suppress the immune response to homografts has not been ...
Nathan P. Couch, William J. Curran, Francis D. Moore   +2 more
openaire   +5 more sources