Results 131 to 140 of about 69,335 (249)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Penis "En Bloc": From Reproducible Harvesting to Transplantation in a Cadaver study. [PDF]

Eur Urol Open Sci
Fourel M, Morel-Journel N, Badet L, Ruffion A, Carnicelli D, Chaffanjon P, Fiard G, Airoldi S, Boucher F, Neuville P.   +9 more
europepmc   +1 more source

Safe corridor for fibular transfixation wire in relation to common peroneal nerve: A cadaveric analysis [PDF]

, 2018
Ranjit Kumar Baruah, Sreedharan Harikrishnan, Jishnu Prakash Baruah   +2 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Towards clinical magnetic particle imaging: safety measurements of medical implants in a human cadaver model. [PDF]

Commun Eng
Wegner F, Friedrich T, Elfers PN, Kleefeldt F, Peter D, Gruschwitz P, Reichl T, Günther J, Kampf T, Rückert MA, Behr VC, Buzug TM, Kloeckner R, Barkhausen J, Bley TA, Vogel P, Hartung V.   +16 more
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Emotional distress among medical students before and after the first exposure to a full cadaver dissection: a quantitative study using DASS-21. [PDF]

Med Educ Online
Salama MNF, Abdelkhalek AM, El Nayal MA, Rathan R, Sayegh MG, Mady M.   +5 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Suprascapular Artery Variability in a Zambian Cadaveric Population: Anatomical Observations and Their Clinical Significance. [PDF]

Cureus
Sethy S, Nambule Syamuleya V, Kumar Singh A, Joshi KJ, Jasani K.   +4 more
europepmc   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source