Results 221 to 230 of about 174,303 (342)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Integration of Simulated Thoracentesis Using Thiel-preserved Cadavers in the Teaching of Thoracic Anatomy for Learning Unit III Medical Students: An Innovative Learning Strategy. [PDF]

Acta Med Philipp
Abdulla AJA, Baticulon RE, Genuino RF, Sotalbo CPJ, Tecson JV.   +4 more
europepmc   +1 more source

Effect of Splenectomy on First Cadaver Kidney Transplants

, 1980
Frank P. Stuart, Craig R. Reckard, Beverley L. Ketel, James A. Schulak   +3 more
openalex   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

New Microcannulation Technique for Imaging Contrast and Drug Delivery via the Lymphatics. [PDF]

Plast Reconstr Surg Glob Open
Suami H.
europepmc   +1 more source

COMPARISON OF PULSATILE MACHINE PERFUSION WITH COLD STORAGE FOR CADAVER KIDNEY PRESERVATION

, 1984
NULL AUTHOR_ID
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Effect of Kidney Transplant Type on Coronary Endothelial Function in Individuals with Chronic Kidney Disease. [PDF]

Ann Transplant
Guz G, Karaoğlu RO, Kumaş Solak S, Demirgan EB, Demirgan S.   +4 more
europepmc   +1 more source

MANNITOL AS AN INDISPENSABLE CONSTITUENT OF AN INTRAOPERATIVE HYDRATION PROTOCOL FOR THE PREVENTION OF ACUTE RENAL FAILURE AFTER RENAL CADAVERIC TRANSPLANTATION

, 1987
P. L. J. VAN VALENBERG, A. J. Hoitsma, R.G.W.L. Tiggeler, J. H. M. Berden, H. J. J. VAN LIER, R. A. P. Koene   +5 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source