Results 251 to 260 of about 234,741 (400)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Ultrasound-guided Emergency Pericardiocentesis Simulation on Human Cadavers: A Scoping Review. [PDF]
West J Emerg MedÜnlü L +7 more
europepmc +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Preparation of plasminogen activator from vascular trees of human cadavers
, 1976 Nobuo Aoki
openalex +2 more sources
The pretreatment principle in renal transplantation as illustrated by thoracic duct drainage [PDF]
, 1980 Koep, LJ, Starzl, TE, Weil, R
core
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
From Cadaver to Clinic: Transforming First-Year Anatomy Education Through Early Ultrasound Integration. [PDF]
CureusSehgal G, Aggarwal N.
europepmc +1 more source