Results 71 to 80 of about 65,963 (312)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Perceptions and Struggle of Corneal Donation and Transplants: You can see the World even after Death

Pakistan Journal of Medical Research, 2021
Objective: To assess knowledge, opinion and perception of the general population regarding corneal donation and transplantation. Another objective was to investigate desires, fulfilment, battle and results of patient’s experiences of Corneal Transplant ...
Sana Abbas, Aisha Rafique
doaj  

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

The Cadaver on the Cover

Academic Medicine, 2010
Dennis DePace, Michelle Paff
openaire   +6 more sources

Contamination of cadavers by saccharomyces cerevisiae [PDF]

, 1920
Ralph A. Kordenat
openalex   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Knowledge, Attitude and Willingness Towards Organ Donation among People Attending Out Patient Departments of a Tertiary Care Hospital, West Bengal: A Cross-sectional Study [PDF]

Journal of Caring Sciences
Introduction: Organ donation rate in India is lower compared to many developed countries. A shortage of organs for individuals in need persists, as people are hesitant to donate.
Bobby Syiemlieh, Obangkokla O, Mousumi Khatun, Poonam Joshi, Latha T, Jamuna R Rani, Ajay Mallick   +6 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Anatomical Studies Evaluating Pediatric Regional Anesthesia: A Scoping Review

Children
Background: Pediatric regional anesthesia has been driven by the gradual rise in the adoption of opioid-sparing strategies and the growing concern over the possible adverse effects of general anesthetics on neurodevelopment.
Lucas Ferreira Gomes Pereira, Ricardo Vieira Carlos, Albert van Schoor, Adrian Bosenberg, Natália Mariana Silva Luna, Rebeca da Costa Silva, Bianca de Fátima Bertanha, Maria José Carvalho Carmona, Vinícius Caldeira Quintão   +8 more
doaj   +1 more source