Results 21 to 30 of about 71,823 (248)

Analyzing caesarean sections through the Robson classification in Nigeria: a prospective nationwide study in referral level facilitiesResearch in context

EClinicalMedicine
Summary: Background: Over the past 30 years, there has been increased concern on rising caesarean section rates. However, the absence of reliable data on appropriateness of caesarean section for women in many countries, including Nigeria, poses a ...
Tina Lavin, Amaka N. Ocheke, Ana Pilar Betran, Abiodun S. Adeniran, Eziamaka Ezenkwele, Duum C. Nwachukwu, Luz Gibbons, Aisha Abdurrahman, Sulaiman Muhammad Deneji, Akpanika Chinyere, Adewale Ashimi, Rais Ibraheem, Odward Elusoji Jagun, Innocent Anayochukwu Ugwu, Olufemi Aworinde, Agada Egwu, Sunday Ochigbo, Timothy A.O. Oluwasola, Aniekan Abasiattai, Anthonia Inibokun Njoku, Lawal Magaji, Peter Aboyeji, Hadiza Galadanci, Calvin Chama, Saturday Etuk, Joseph Ikechebelu, Olubukola Adesina, Jamilu Tukur   +27 more
doaj   +1 more source

Does attendance of a prenatal education course reduce rates of caesarean section on maternal request? A questionnaire study in a tertiary women hospital in Shanghai, China

BMJ Open, 2019
ObjectiveCaesarean section rates have significantly increased worldwide. China has a caesarean rate of 46%, with a moderate contribution of caesarean section on maternal request.
Qi Chen, Yifei Gao, Yunhui Tang, Mancy Tong   +3 more
doaj   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Contribution of women's preference to the overuse of caesarean sections: A propensity score matching analysis based on a multi-country cross-sectional survey, as part of the QUALI-DEC project.

PLoS ONE
IntroductionMaternal request for caesarean section has often been cited to justify the increasing caesarean section rates worldwide. However, we lack evidence on the impact of women's preference for caesarean section on this dramatic tendency.
Camille Etcheverry, Ana Pilar Betrán, Marion Ravit, Charles Kaboré, Pisake Lumbiganon, Guillermo Carroli, Quoc Nhu Hung Mac, Celina Gialdini, Alexandre Dumont, QUALI-DEC research group   +9 more
doaj   +1 more source

Rising Rates of Caesarean Section in Urban Nepal

Journal of Nepal Health Research Council, 2019
The rising rate of caesarean section in urban Nepal is alarming as the lack of access for women in rural areas to emergency obstetric care, putting lives at risk. The latter is referred to as ‘Too little too late’.
Sulochana Dhakal Rai, Pramod Raj Regmi, Edwin van Teijlingen, Juliet Wood, Ganesh Dangal, Keshar Bahadur Dhakal   +5 more
doaj   +1 more source

Caesarean section rates from Malaysian tertiary hospitals using Robson’s 10-group classification

BMC Pregnancy and Childbirth, 2020
Background Rising caesarean section rates is a concern worldwide. This study aimed to use Robson’s ten group classification to identify which groups of women were contributing most to the rising caesarean section rates in Malaysian tertiary hospitals and
Shamala Devi Karalasingam, Ravichandran Jeganathan, Ravindran Jegasothy, Daniel D. Reidpath   +3 more
doaj   +1 more source

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo   +9 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

WHO Global Survey on Maternal and Perinatal Health in Latin America: classifying caesarean sections

Reproductive Health, 2009
Background Caesarean section rates continue to increase worldwide with uncertain medical consequences. Auditing and analysing caesarean section rates and other perinatal outcomes in a reliable and continuous manner is critical for understanding reasons ...
Faúndes Anibal, Velasco Alejandro, Narváez Alberto, Langer Ana, Torloni Maria R, Carroli Guillermo, Widmer Mariana, Wojdyla Daniel, Souza João P, Merialdi Mario, Robson Michael, Gulmezoglu A Metin, Betrán Ana P, Acosta Arnaldo, Valladares Eliette, Romero Mariana, Zavaleta Nelly, Reynoso Sofia, Bataglia Vicente   +18 more
doaj   +1 more source