Abstract Objective This study evaluated the pharmacokinetics of zavegepant in human breast milk and plasma following a single, 10 mg dose of zavegepant nasal spray. Background Zavegepant nasal spray is a member of the gepant class of medications; small molecule inhibitors of the calcitonin gene‐related peptide receptor.
Abhijeet Jakate +9 more
wiley +1 more source
The Effects of Caffeine and Resistance Exercise on Pulse Wave Reflection in Resistance-Trained Women. [PDF]
Kearney SG +7 more
europepmc +1 more source
Understanding Nurses' Needs Regarding Tailored, Evidence‐Based Sleep Education and Training
ABSTRACT Aim Identify desired training content for shift‐working nurses to improve their sleep and fatigue. Design A descriptive qualitative design. Methods We recruited night shift nurses (N = 23) to provide feedback during virtual focus groups/interviews. Data collection occurred in the U.S. between March and June 2024.
Beverly M. Hittle +7 more
wiley +1 more source
Total caffeine intake is associated with lower serum α-Klotho and may impact its detection accuracy: Evidence from NHANES 2007 to 2016 and molecular docking. [PDF]
Shi FE +5 more
europepmc +1 more source
Elevated Salivary Theobromine and Long‐Term Improvement of Periodontal Health in Two Cohort Studies
ABSTRACT Background Theobromine, a methylxanthine mainly found in chocolate, has been suggested to possess various health‐promoting properties. This study aimed to investigate the long‐term effect of salivary theobromine levels on periodontitis severity using 7‐ and 10‐year follow‐up data from the prospective Studies of Health in Pomerania (SHIP‐TREND ...
Thomas Kocher +8 more
wiley +1 more source
Effects of caffeine on neuroinflammation in anxiety and depression: a systematic review of rodent studies. [PDF]
da Silva Neves L +4 more
europepmc +1 more source
The exposomal imprint on rosacea: More than skin deep
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki +3 more
wiley +1 more source
Caffeine consumption patterns, motivations, and adverse effects among Brazilian esports players: a cross-sectional study. [PDF]
Abhulime EWM +4 more
europepmc +1 more source
Global consensus on the management of melanin hyperpigmentation disorders
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron +9 more
wiley +1 more source

