Results 241 to 250 of about 204,221 (349)

cag out

keg vFinally, but .....maintaining his sobriety to the bitter end, he would _cag out_, i.e., succumb to demon rum.DNE-citUsed IUsed I2Used Icag, cagging or kegging, cagged, keg/cag out, KEEL OUTChecked by Raji Sreeni on Mon 29 Jun 2015; An ellipsis ...

core  

Hyperhomocysteinemia and Vitamin B Deficiency as Potential Aggravating Factors in Huntington's Disease: A Prospective Monocentric Study

Movement Disorders, EarlyView.
Abstract Background Although not confirmed, some studies have suggested that elevated homocysteine levels are common in patients with Huntington's disease (HD). Its clinical relevance remains unclear. Objectives We aimed to assess vitamin B and homocysteine levels in HD patients and explore the relationships among hyperhomocysteinemia, vitamin B ...
Salomé Puisieux, Elise Pourié, Céline Bonnet, Lucie Hopes, Solène Frismand, Myriam Bronner, Virginie Roth, Marion Wandzel, Natacha Sloboda, Laetitia Lambert, Abderrahim Oussalah, Amélia Julien, Irina Rotaru, Rosa‐Maria Guéant‐Rodriguez, Jean Louis Guéant, Carine Bossenmeyer‐Pourié, Mathilde Renaud   +16 more
wiley   +1 more source

Gastric Microbiota Dysbiosis and Microbiome-Based Interventions in Chronic Atrophic Gastritis. [PDF]

Nutrients
Li A, He Y, Walayat B, Saleem A, Zhao J, Wang Q, Zhang X, Li C, Liu Y, Lu S, Li M.   +10 more
europepmc   +1 more source

DNA Repair Pathway Variants Are Enriched in Individuals with Biallelic AAGGG CANVAS and RFC1‐Related Disease

Movement Disorders, EarlyView.
Abstract Background Cerebellar ataxia, neuropathy and vestibular are flexia syndrome (CANVAS) and RFC1‐related disease are most commonly caused by biallelic AAGGG repeat expansions in RFC1. The high population frequency of this expansion compared to the frequency of CANVAS suggests incomplete penetrance.
Xuemin Wang, Liam G. Fearnley, Kayli C. Davies, Penny Snell, Stuart Lee, Victoria E. Jackson, Justin Read, Michael Milton, Ian H. Harding, Martin B. Delatycki, David J. Szmulewicz, Paul J. Lockhart, Melanie Bahlo, Haloom Rafehi   +13 more
wiley   +1 more source

Discovery of a mutation-containing circRNA in polyglutamine disease through systematic analysis of RNAs with CAG repeats. [PDF]

RNA Biol
Pawlik W, Woźna-Wysocka M, Jazurek-Ciesiołka M, Dulski J, Witkoś TM, Ciołak A, Kozłowska E, Kościańska E, Bartelt LC, Philippe J, Sławek J, Świtoński PM, La Spada AR, Fiszer A.   +13 more
europepmc   +1 more source

Cytosine deamination and base excision repair cause R-loop–induced CAG repeat fragility and instability in Saccharomyces cerevisiae

Proceedings of the National Academy of Sciences of the United States of America, 2017
Xiaofeng A. Su, C. Freudenreich
semanticscholar   +1 more source

Early Longitudinal Brain Network Changes in Huntington's Disease Before Clinical Motor Onset

Movement Disorders, EarlyView.
Abstract Background Longitudinal studies of seed‐based functional connectivity (SBFC) in young adult Huntington's disease gene‐expanded (HDGE) individuals are rare, and none, to our knowledge, have examined adult cohorts decades from predicted clinical motor diagnosis.
Michela Leocadi, Nicola Z. Hobbs, Mena Farag, Michael J. Murphy, Kate Fayer, Olivia Thackeray, Harry Knights, James B. Rowe, Trevor W. Robbins, Barbara J. Sahakian, Geraint Rees, Rachael I. Scahill, Sarah J. Tabrizi, Christelle Langley   +13 more
wiley   +1 more source

2013 Canadian Association of Gastroenterology Educational Needs Assessment Report

Canadian Journal of Gastroenterology, 2013
Craig Render
doaj   +1 more source

Network-based stratification of allele-specific expression reveals patient subgroups in Huntington's disease. [PDF]

Bioinformatics
van Beek D, Iyer A, Ehrhart F, Evelo CT, de Kok TM, Arts ICW, Adriaens ME, Kutmon M.   +7 more
europepmc   +1 more source

Expanded ATXN3 CAG Repeat is Stable in Human Purkinje Cells

Movement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia type 3 (SCA3) is a neurodegenerative disorder caused by an abnormally long polyglutamine‐encoding CAG repeat in the ATXN3 gene. Objectives We aimed to determine whether somatic expansion of the mutant ATXN3 (mATXN3) CAG repeat is present in the output cell of the cerebellar cortex, the Purkinje cell (PC), in ...
Hasnahana Chetia, Laura Kus, Erika Sipos, Nathaniel Heintz, Kert Mätlik   +4 more
wiley   +1 more source