Results 161 to 170 of about 288,938 (268)

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

Advanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang, Meng‐Meng Liu, Yu‐Chen Zhao, Jia‐Yi Li, Wen Li, Xin Yu   +5 more
wiley   +1 more source

Environmental contamination and internal organ colonization by Salmonella Enteritidis in experimentally infected cage-free layer pullets reared in-place or relocated after simulated transport. [PDF]

Poult Sci
Gast RK, Garcia JS, Guraya R, Jones DR, Hurley-Bacon AL, Karcher DM.   +5 more
europepmc   +1 more source

Polymer‐Grafted Cu(II) Metal–Organic Polyhedra as Scalable, Melt‐Processable Porous Materials

Advanced Science, EarlyView.
The use of a direct synthetic route to obtain polymer‐grafted Cu(II)‐based metal–organic polyhedra gives rise to a low‐cost and scalable cage. This material combines low‐temperature melting, achieving phase changes while preserving cage integrity, and high CO2 uptake exceeding 0.6 mmol g−1.
Alba Cortés‐Martínez, Francisco Sánchez‐Férez, José A. Suárez del Pino, Sergio Royuela, Félix Zamora, Daniel Maspoch, Arnau Carné‐Sánchez   +6 more
wiley   +1 more source

Environment shapes gut microbiome and determines susceptibility to DSS-colitis in <i>Adamdec1^-/-</i> mice. [PDF]

Front Immunol
Kumagai T, Rath S, Fan S, Rahman FZ, Smith AM.   +4 more
europepmc   +1 more source

Molecular‐Level Pore Engineering for Precise Separation via Active Solvent‐Mediated Interfacial Polymerization

Advanced Science, EarlyView.
We demonstrate that microemulsion solvents can actively template molecular‐level pores within selective layer during interfacial polymerization. By creating localized quasi‐homogeneous polymerization zones, the membrane achieved a 7.1‐fold enhancement in water permeance with increased selectivity.
Feng Li, R. M. G. Rajapakse, Yuxin Mou, Deyin Hou, Min Yang   +4 more
wiley   +1 more source

Immersive Social Interaction Assay (ISIA) for Studying Voluntary and Long-Term Social Behavior in Mice. [PDF]

Bio Protoc
Crane A, Sorvino Mancini E, Eban-Rothschild A.   +2 more
europepmc   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Multi-Plant Screening and Controlled Evaluation of Two Selected Plant Species Against <i>Tuta absoluta</i> (Meyrick). [PDF]

Insects
Mshora A, Mng'ong'o M, Santos L, Chiconela T.   +3 more
europepmc   +1 more source