Results 71 to 80 of about 798,396 (336)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Mixed Cages

Graphs and Combinatorics, 2019
We introduce the notion of a $[z, r; g]$-mixed cage. A $[z, r; g]$-mixed cage is a mixed graph $G$, $z$-regular by arcs, $r$-regular by edges, with girth $g$ and minimum order. In this paper we prove the existence of $[z, r ;g]$-mixed cages and exhibit families of mixed cages for some specific values.
Araujo-Pardo, G., Hernández-Cruz, C., Montellano-Ballesteros, J. J.   +2 more
openaire   +2 more sources

Methanotroph activity and connectivity between two seep systems north off Svalbard

Frontiers in Earth Science
Understanding methane flux dynamics in Arctic cold seep systems and the influence of oceanic currents on microbial methane-oxidizing bacteria (MOB) is crucial for assessing their impact on Arctic methane emissions.
Tim R. de Groot, Dimitri Kalenitchenko, Dimitri Kalenitchenko, Manuel Moser, Claudio Argentino, Giuliana Panieri, Matteus Lindgren, Knut Ola Dølven, Benedicte Ferré, Mette M. Svenning, Mette M. Svenning, Helge Niemann, Helge Niemann, Helge Niemann   +13 more
doaj   +1 more source

Comparison of the outcomes of cage-stand-alone with cage-with-plate fixation in one level and two levels for treating cervical disk diseases

Journal of Craniovertebral Junction and Spine, 2018
Introduction: Anterior cervical discectomy and fusion (ACDF) surgery is an accepted method for many spinal cord abnormalities. The purpose of this study was to evaluate the outcomes of treating patients with spinal cord lesions at one level or two levels
Mohammadreza Etemadifar, Ali Andalib, Hossein Shafiee, Milad Kabiri Samani   +3 more
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Clinical efficiency of a new allograft cervical cage in treatment of cervical spondylosis

Di-san junyi daxue xuebao, 2019
Objective To evaluate the efficacy and reliability of a novel allograft cervical cage in treatment of cervical spondylosis, and observe the effect of subsidence on clinical outcome.
FANG Qing, LI Yang, WU Wenjie, LIU Xun
doaj   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Faraday cage angled-etching of nanostructures in bulk dielectrics

, 2016
For many emerging optoelectronic materials, heteroepitaxial growth techniques do not offer the same high material quality afforded by bulk, single-crystal growth.
Burek, Michael J., Latawiec, Pawel, Lončar, Marko, Sohn, Young-Ik   +3 more
core   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Thermodynamics of glasses: a first principle computation

, 1998
We propose a first principle computation of the thermodynamics of simple fragile glasses starting from the two body interatomic potential. A replica formulation translates this problem into that of a gas of interacting molecules, each molecule being ...
A. Crisanti, A. Crisanti, A. W. Kauzmann, B. Bernu, C. A. Angell, D. J. Gross, E. Marinari, E. Marinari, G. Adams, G. Parisi, G. Parisi, G. Toulouse, Giorgio Parisi, J. H. Gibbs, J. Kurchan, J. N. Roux, J.-P. Bouchaud, M. Mézard, Marc Mézard, P. Chandra, R. Monasson, S. Caracciolo, S. Franz, S. Franz, T. Keyes, T. R. Kirkpatrick, T. R. Kirkpatrick, T. R. Kirkpatrick, T. R. Kirkpatrick, W. Kob, Y. Wan   +30 more
core   +3 more sources