Results 51 to 60 of about 97,536 (245)

Congenital adrenal hyperplasia: Treatment and outcomes

Indian Journal of Endocrinology and Metabolism, 2013
Congenital adrenal hyperplasia (CAH) describes a group of autosomal recessive disorders where there is impairment of cortisol biosynthesis. CAH due to 21-hydroxylase deficiency accounts for 95% of cases and shows a wide range of clinical severity ...
Mahdi Kamoun, Mouna Mnif Feki, Mohamed Habib Sfar, Mohamed Abid   +3 more
doaj   +1 more source

Health-related quality of life of female patients with congenital adrenal hyperplasia in Malaysia

Health and Quality of Life Outcomes, 2020
Background This study investigates the health-related quality of life (HRQOL) of female patients with congenital adrenal hyperplasia (CAH) in Malaysia. The objectives were to attain socio-demographic and medical data on these Malaysian females with CAH ...
Ani Amelia Zainuddin, Sonia Regina Grover, Nur Azurah Abdul Ghani, Loo Ling Wu, Rahmah Rasat, Mohd. Rizal Abdul Manaf, Khadijah Shamsuddin, Zaleha Abdullah Mahdy   +7 more
doaj   +1 more source

The Application of Principal Component Analysis on Clinical and Biochemical Parameters Exemplified in Children With Congenital Adrenal Hyperplasia

Frontiers in Endocrinology, 2021
PurposePrincipal component analysis (PCA) is a mathematical model which simplifies data into new, combined variables. Optimal treatment of pediatric congenital adrenal hyperplasia (CAH) remains a challenge and requires evaluation of all biochemical and ...
Marie Lindhardt Ljubicic, Marie Lindhardt Ljubicic, Andre Madsen, Andre Madsen, Andre Madsen, Anders Juul, Anders Juul, Kristian Almstrup, Kristian Almstrup, Trine Holm Johannsen, Trine Holm Johannsen   +10 more
doaj   +1 more source

Sticky Yet Slippery: Molecular Ordering Reconciles Bubble‐Surface Affinity With Ultralow Friction at the Nanoscale

Advanced Science, EarlyView.
By engineering the molecular order and thickness of PDMS layers, we reconcile the stickiness and slipperiness during bubble transport. AFM measurements and MD simulations further reveal how these nanoscale architectures tune hydrophobic interaction FHB and friction force f.
Shishuang Zhang, Jiajun Li, Huadong Tian, Zhoujie Wang, Chenyu Qiao, Jingyi Wang, Lei Xie, Hongbo Zeng   +7 more
wiley   +1 more source

Ultralow-dose dexamethasone to preserve endogenous cortisol stress response in nonclassical congenital adrenal hyperplasia: A new promising treatment [PDF]

, 2014
Introduction: Nonclassical congenital adrenal hyperplasia (CAH) is characterized by sufficient cortisol and aldosterone production at the cost of androgen overproduction.
Akker, E.L.T. (Erica) van den, Kaay, D.C.M. (Danielle) van der   +1 more
core   +1 more source

The Age at Onset of LRRK2 p.Gly2019Ser Parkinson's Disease Across Ancestries and Countries of Origin

Annals of Neurology, EarlyView.
Objectives The objective of this study was to elucidate differences in the cumulative incidence of Leucine‐rich repeat kinase 2 (LRRK2) p.Gly2019Ser‐related Parkinson's disease (PD; LRRK2‐PD) between ancestries and countries. Methods We included 922 unrelated p.Gly2019Ser variant carriers (affected = 762 and unaffected = 160) from the Global Parkinson ...
Theresa Lüth, Björn‐Hergen Laabs, Sebastian Sendel, Inke R. König, Amke Caliebe, Alastair J. Noyce, Laurel A. Screven, Soraya Bardien, Matthew Farrer, Faycel Hentati, Rim Amouri, Christine Klein, Samia Ben Sassi, Joanne Trinh, Global Parkinson's Genetics Program (GP2)   +14 more
wiley   +1 more source

Untreated Congenital Adrenal Hyperplasia with 17-α Hydroxylase/17,20-Lyase Deficiency Presenting as Massive Adrenocortical Tumor [PDF]

Endocrinology and Metabolism, 2015
Congenital adrenal hyperplasia (CAH) with 17α-hydroxylase/17,20-lyase deficiency is usually characterized by hypertension and primary amenorrhea, sexual infantilism in women, and pseudohermaphroditism in men. hypertension, and sexual infantilism in women
Su Jin Lee, Je Eun Song, Sena Hwang, Ji-Yeon Lee, Hye-Sun Park, Seunghee Han, Yumie Rhee   +6 more
doaj   +1 more source

Magnetic tuning of ultracold barrierless chemical reactions [PDF]

, 2014
While attaining external field control of bimolecular chemical reactions has long been a coveted goal of physics and chemistry, the role of hyperfine interactions and dc magnetic fields in achieving such control has remained elusive.
Tscherbul, Timur V., Kłos, Jacek
core   +5 more sources

Modern competency‐based teaching of human sexual development

Anatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler, Alessandro Bilella, Christian M. Hammer   +2 more
wiley   +1 more source

CEBPB promotes transformation of endometrial complex atypical hyperplasia to endometrial cancer

BMC Cancer
Background As the precursor malignancy of endometrial cancer (EC), about 50% of endometrial complex atypical hyperplasia (CAH) will eventually progress to EC. Elucidating the underlying transformation mechanisms could aid in disease management.
Jiahong Tan, Lin Zhao, Daoqi Wang, Xiaodie Wu, Yongxiang Bi, Hanying Wang, Na Ma, Dehong Yang, Wei Dong, Jie Zhang   +9 more
doaj   +1 more source