Results 51 to 60 of about 14,518 (334)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Didaktik för naturvetenskap och hållbar utveckling - Fem former av demokratiskt deltagande
Education for science and Sustainable Development - Four forms of Democratic Participation.

Nordina: Nordic Studies in Science Education, 2019
Education is often argued as crucial to reverse development towards a more fair and sustainable world. This article uses a wide range of research and literature in the field of education for sustainable development, to discuss an educational, ‘didactic’,
Iann Lundegård, Cecilia Caiman
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Parentage test in broad-snouted caimans (Caiman latirostris, Crocodylidae) using microsatellite DNA

Genetics and Molecular Biology, 2009
In this study, microsatellite markers, developed for Alligator mississipiensis and Caiman latirostris, were used to assess parentage among individuals from the captive colony of Caiman latirostris at the University of São Paulo, in Piracicaba, São Paulo,
Rodrigo B. Zucoloto, Luciano M. Verdade, Priscilla M.S. Villela, Luciana C.A. Regitano, Luiz L. Coutinho   +4 more
doaj  

Determination of Hematological Values of Common Crocodile (Caiman Crocodilus fuscus) in Captivity in the Magdalena medio of Colombia

Acta Biológica Colombiana, 2020
Caiman zoo breeding (Caiman crocodilus fuscus) has been developing with greater force in Colombia since the 90s. It is essential to evaluate the physiological ranges of the species to be able to assess those situations in which their health is threatened.
Juana Valentina Grijalba Otálora, Ekin Josué Forero Rojas, Angie Fernanda Contreras, Julio Cesar Vargas, Roy Jose Andrade   +4 more
doaj   +1 more source

Intraspecific isotopic niche variation in broad-snouted caiman (Caiman latirostris)

Isotopes in Environmental and Health Studies, 2013
Strategies to minimise intraspecific competition are common in wild animals. For example, individuals may exploit food resources at different levels of the food chain. Analyses of stable isotopes are particularly useful for confirming variations in an intraspecific niche because the chemical composition of animals tends to reflect both the food ...
Marques, Thiago S., Lara, Neliton R. F., Bassetti, Luís A. B., Piña, Carlos Ignacio, Camargo, Plínio B., Verdade, Luciano M.   +5 more
openaire   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Better use of caiman yacare carcass and physical-chemical characterization of mechanically separated meat

Ciência Rural
: The captive breeding of the Pantanal caiman (Caiman yacare) offers great potential for the full use of all the component parts of the animal.
Gilmar Borges de Paiva, Elisa Rafaela Bonádio Bellucci, Marco Antônio Trindade, Javier Teles Romero, Andrea Carla da Silva Barretto   +4 more
doaj   +1 more source

Aspectos ecológicos de la anidación de Caiman crocodilus chiapasius (Bocourt, 1876) en la reserva de la biosfera La Encrucijada, México [PDF]

Animal Biodiversity and Conservation, 2016
Ecological aspects of nesting in Caiman crocodilus chiapasius (Bocourt 1876) in La Encrucijada Biosphere Reserve, Mexico Studies on caiman, Caiman crocodilus chiapasius, in Mexico are scarce.
González–Desales, G. A., Monroy–Vilchis, O., Charruau, P., Zarco–González, M. M.   +3 more
doaj  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source