Results 41 to 50 of about 1,513,882 (174)

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

Cell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang, Shijie Lv, Lejia Li, Jirong Xie, Zhengguo Cao   +4 more
wiley   +1 more source

Novel and emerging skin carcinomas and adnexal tumours

Histopathology, EarlyView.
The present review aims to provide an overview of the main emerging skin epithelial tumours, with particular emphasis on salivary gland analogue sweat gland tumours and poorly differentiated carcinomas. Epidermal and adnexal tumours of the skin constitute a complex and heterogeneous group of neoplasms, with distinct morphology and behaviour.
Thibault Kervarrec, Maxime Battistella, Nicolas Macagno   +2 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Squamous Odontogenic Tumor: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective Squamous odontogenic tumor is a rare benign epithelial odontogenic neoplasm whose overlapping features with other odontogenic lesions may hinder diagnosis and management. This systematic review analyzed clinical, radiographic, histopathological characteristics and treatment outcomes of SOT.
Paula Sousa Lopes de Cascaes, Licia Pacheco Teixeira, Andresa Borges Soares, Izabel Regina Fischer Rubira‐Bullen, Monikelly Carmo Narchini do Nascimento, José Luiz Cintra Junqueira, Mariana Quirino Silveira Soares   +6 more
wiley   +1 more source

Pindborg tumor

Contemporary Clinical Dentistry, 2016
Calcifying epithelial odontogenic tumor (CEOT), also known as Pindborg tumor, is a rare odontogenic epithelial neoplasm. So far, nearly 200 cases have been reported in the literature.
Santhosh Kumar Caliaperoumal, S Gowri, J Dinakar   +2 more
doaj   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

ADENOMATOID ODONTOGENIC TUMOR ASSOCIATED WITH CALCIFYING EPITHELIAL ODONTOGENIC TUMOR: A CASE REPORT

, 2021
Adenomatoid Odontogenic Tumors (AOT) make up 3% of all odontogenic tumors. The most conspieuous feature of this tumor is nodules or wholes of spindle-shaped of cuboidal epithelial cells.
Selvi, Fırat, Bilgic, Bilge, Kasymova, Zamira, Demiryont, Misten, Kaynar, Ayfer   +4 more
core  

A rare presentation of hybrid odontogenic tumor involving calcifying cystic odontogenic tumor and plexiform ameloblastoma

Contemporary Clinical Dentistry, 2013
A hybrid odontogenic tumor comprising two distinct lesions is extremely rare. We presented a hybrid odontogenic tumor composed of a calcifying cystic odontogenic tumor (CCOT) and a plexiform ameloblastoma.
Snehal S Chaubey, Sunil S Mishra, Shirish S Degwekar, Saujanya Chaubey   +3 more
doaj   +1 more source