Results 11 to 20 of about 29,117 (272)

Calcinosis Cutis and Calciphylaxis in Autoimmune Connective Tissue Diseases

open access: yesVaccines, 2023
Calcinosis represents a severe complication of several autoimmune disorders. Soft-tissue calcifications have been classified into five major types: dystrophic, metastatic, idiopathic, iatrogenic, and calciphylaxis.
Ilaria Mormile   +5 more
doaj   +2 more sources

Role of mitochondria in the myopathy of juvenile dermatomyositis and implications for skeletal muscle calcinosis

open access: yesJournal of Autoimmunity, 2023
Objectives: To elucidate mechanisms contributing to skeletal muscle calcinosis in patients with juvenile dermatomyositis. Methods: A well-characterized cohorts of JDM (n = 68), disease controls (polymyositis, n = 7; juvenile SLE, n = 10, and RNP ...
Bhargavi Duvvuri   +11 more
semanticscholar   +1 more source

Development of a computed tomography calcium scoring technique for assessing calcinosis distribution, pattern and burden in dermatomyositis.

open access: yesRheumatology, 2023
OBJECTIVES To utilize whole-body computed tomography (CT) imaging and calcium scoring techniques as tools for calcinosis assessment in a prospective cohort of patients with adult and juvenile dermatomyositis (DM and JDM, respectively).
Briana A Cervantes   +5 more
semanticscholar   +1 more source

Management of Calcinosis Cutis in Rheumatic Diseases

open access: yesJournal of Rheumatology, 2022
Calcinosis (hydroxyapatite and calcium phosphate crystal deposition) within the extracellular matrix of the dermis and subcutaneous tissue is a frequent manifestation of adult and pediatric systemic autoimmune rheumatic diseases, specifically systemic ...
H. Elahmar, B. Feldman, S. Johnson
semanticscholar   +1 more source

CREST Syndrome in Systemic Sclerosis Patients – Is Dystrophic Calcinosis a Key Element to a Positive Diagnosis?

open access: yesJournal of Inflammation Research, 2022
Introduction CREST syndrome is a clinical entity associated with systemic sclerosis, which meets at least three of the five clinical features: calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Carmen Bobeica   +16 more
semanticscholar   +1 more source

Cumulative Disease Damage and Anti-PM/Scl Antibodies Are Associated with a Heavy Burden of Calcinosis in Systemic Sclerosis.

open access: yesRheumatology, 2022
OBJECTIVES Ectopic calcification (calcinosis) is a common complication of systemic sclerosis, but a subset of systemic sclerosis patients has a heavy burden of calcinosis. We examined whether there are unique risk factors for a heavy burden of calcinosis,
Carrie Richardson   +7 more
semanticscholar   +1 more source

Local, non-systemic, and minimally invasive therapies for calcinosis cutis: a systematic review

open access: yesArchives of Dermatological Research, 2021
Calcinosis cutis is a deposition of calcium in the skin and subcutaneous tissue, often accompanied by pain, reduced mobility, and chronic infections. Limited evidence is available about the feasibility and efficacy of therapies alternative to systemic ...
Joanna Nowaczyk   +2 more
semanticscholar   +1 more source

Bisphosphonates for the Treatment of Calcinosis Cutis—A Retrospective Single-Center Study

open access: yesBiomedicines, 2021
(1) Background: Calcinosis cutis is a frequent symptom of autoimmune connective tissue diseases leading to pain, transcutaneous expulsion of calcified material and bacterial superinfection.
Lilian Rauch   +4 more
semanticscholar   +1 more source

Subcutaneous calcinosis: Is it different between systemic sclerosis and dermatomyositis?

open access: yesJournal of Scleroderma and Related Disorders, 2021
Calcinosis cutis is the deposition of insoluble calcium in the skin and subcutaneous tissues. It is a manifestation of several autoimmune connective tissue diseases, most frequently with systemic sclerosis and juvenile dermatomyositis, followed by adult ...
A. Valenzuela, L. Chung
semanticscholar   +1 more source

Extensive Calcinosis in an Adult Nigerian Woman with Dermatomyositis

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2015
Objectives: Extensive calcinosis in a patient with dermatomyositis is a rare clinical presentation in adults. The aim of this report is to present the clinical and radiographic features of a 25-year-old woman with dermatomyositis and extensive calcinosis.
Olufemi Adelowo   +3 more
doaj   +1 more source

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