Hierarchical Structure and Fabrication of Functionally Graded Biointerfaces in the Mussel Byssus
The byssus is a fibrous protein‐based holdfast consisting of mechanically distinct interfaces, which mussels use to anchor their soft living tissue to hard seashore surfaces. Here, multiscale methodologies were used to elucidate the compositional and structural features underlying these functionally graded interfaces and how they are fabricated through
Lucia Youssef +4 more
wiley +1 more source
CaBind_MCNN: Identifying Potential Calcium Channel Blocker Targets by Predicting Calcium-Binding Sites in Ion Channels and Ion Transporters Using Protein Language Models and Multiscale Feature Extraction. [PDF]
Chang YY +4 more
europepmc +1 more source
Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee +3 more
wiley +1 more source
Predictors of Mortality in Adults With Calcium Channel Blocker Toxicity Receiving Extracorporeal Membrane Oxygenation Support: An Extracorporeal Life Support Organization Registry Analysis. [PDF]
Subramanian R +3 more
europepmc +1 more source
Polyelectrolyte scaffold coatings modified with Cu and Fe3O4 nanoparticles regulate neural stem cell behavior in vitro. Increased Fe3O4 content enhances mitochondrial activity and neuronal differentiation, whereas higher Cu levels reduce cell viability.
Anna Grzeczkowicz +5 more
wiley +1 more source
Rationale and Design of a Randomized, Open-Label, Parallel-Group Study of Esaxerenone Versus Angiotensin Receptor Blockers in Older Patients With Uncontrolled Hypertension on Calcium Channel Blocker Monotherapy (ESCORT-HT). [PDF]
Kario K +6 more
europepmc +1 more source
An Injectable Electroactive Hydrogel Engineered for Stable Bioelectronic Interfaces
Injectable electroconductive hydrogels enable soft, conformal, and stable bioelectronic interfaces for electroceutical therapies. A catechol‐modified hyaluronic acid/alginate/edge‐functionalized graphene platform combines wet adhesion, shear‐thinning injectability, tissue‐matched mechanics, and electrochemical functionality.
Ying Zhou +11 more
wiley +1 more source
Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records. [PDF]
Þorsteinsson H +11 more
europepmc +1 more source
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane +4 more
wiley +1 more source
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu +8 more
wiley +1 more source

