Results 51 to 60 of about 947,105 (257)

Antimicrobial potency, prevention ability, and killing efficacy of daptomycin-loaded versus vancomycin-loaded β-tricalcium phosphate/calcium sulfate for methicillin-resistant Staphylococcus aureus biofilms

Frontiers in Microbiology, 2022
Growing evidence has shown that the efficacy of systemic administration of daptomycin for the treatment of methicillin-resistant Staphylococcus aureus (MRSA)-related infections is satisfactory.
Xin Zhang, Xin Zhang, Peng Chen, Peng Chen, Hao-yang Wan, Run-jiu Zhu, Yue Zhou, Ming-rui Song, Nan Jiang, Nan Jiang, Bin Yu, Bin Yu   +11 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X [PDF]

, 2010
Human adenoviruses from multiple species bind to coagulation factor X (FX), yet the importance of this interaction in adenovirus dissemination is unknown.
Angela C Bradshaw, Duffy, Margaret R., Andrew H. Baker, Lynda Coughlan, Coughlan Lynda, Baker Andrew H., van Rooijen, Nico, van Rooijen, N., Nicklin, Stuart A., Margaret R Duffy, Parker, A.L., Kahari, V.M., Alan L Parker, Kähäri Veli-Matti, Stuart A Nicklin, Nico van Rooijen, Andrew H Baker, Coughlan, L., Nicklin Stuart A., Coughlan, Lynda, Kahari, Veli-Matti, Duffy, M.R., Parker Alan L., Bradshaw Angela C., Parker, Alan L., Duffy Margaret R., Bradshaw, Angela C., Bradshaw, A.C., Rooijen, N. van, Veli-Matti Kähäri, Angela C. Bradshaw, Alan L. Parker, Margaret R. Duffy, Stuart A. Nicklin, Baker, Andrew H., Baker, A.H., Nicklin, S.A., van Rooijen Nico   +37 more
core   +3 more sources

Experimental study on the repair of tibial plateau defect

Chinese Journal of Traumatology, 2012
【Abstract】 Objective: To evaluate the effect of autograft bone, allograft bone, calcium sulfate bone cement, and calcium phosphate bone cement on the repair of tibial plateau defect in rabbits.
XU Hai-lin, HAN Na, KOU Yu-hui, WANG Yan-hua, ZHANG Hong-bo, JIANG Bao-guo   +5 more
doaj  

Prediction and Inhibition of Inorganic Salt Formation under Static and Dynamic Conditions – Effect of Pressure, Temperature, and Mixing Ratio

International Journal of Technology, 2016
As a result of waterflooding, inorganic salt precipitation occurs in the different parts of an oil production system, thereby leading to damage of production equipment. Different parameters affect the kinetics of salt precipitation.
Azizollah Khormali, Dmitry G. Petrakov, Anar R. Farmanzade   +2 more
doaj   +1 more source

Calcium Sulfate as Bone Graft Substitute in the Treatment of Osseous Bone Defects, A Prospective Study [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Calcium sulfate belongs to synthetic ceramic group of bone graft substitutes having an osteoconductive property. Calcium sulfate is an easily available, economic bone graft substitute.
Yashavantha Kumar C, Nalini K B, Jagdish Menon, Dilip Kumar Patro, Banerji B H   +4 more
doaj   +1 more source

The antibacterial efficacy of calcium hydroxide–iodophors and calcium hydroxide–barium sulfate root canal dressings on Enterococcus faecalis and Porphyromonas gingivalis in vitro

Dental Journal, 2022
Background: A successful endodontic treatment is inseparable from the right choice of root canal dressing. The right choice of medicaments would result in patient satisfaction. Enterococcus faecalis (E.
Eric Priyo Prasetyo, Devi Eka Juniarti, Galih Sampoerno, Dian Agustin Wahjuningrum, Ananta Tantri Budi, Dyanita Hasri, Evelyn Tjendronegoro   +6 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Competition and coexistence of sulfate-reducing bacteria, acetogens and methanogens in a lab-scale anaerobic bioreactor as affected by changing substrate to sulfate ratio [PDF]

, 2008
The microbial population structure and function of natural anaerobic communities maintained in lab-scale continuously stirred tank reactors at different lactate to sulfate ratios and in the absence of sulfate were analyzed using an integrated approach of
Stams, A.J.M. (author), Muyzer, G., Kuenen, J.G., Gerard Muyzer, Dar, S., Shabir A. Dar, Kleerebezem, R. (author), Kuenen, J.G. (author), Robbert Kleerebezem, Dar, S.A., Alfons J. M. Stams, Stams, A.J.M., Dar, S.A. (author), Kleerebezem, R., J. Gijs Kuenen, Muyzer, G. (author)   +15 more
core   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source