Results 111 to 120 of about 1,447,843 (300)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Calculation of Feynman integrals by difference equations

, 2003
In this paper we describe a method of calculation of master integrals based on the solution of systems of difference equations in one variable. Various explicit examples are given, as well as the generalization to arbitrary diagrams.Comment: LaTex, 10 ...
Laporta, S.
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Solution of plane cascade flow using improved surface singularity methods [PDF]

A solution method was developed for calculating compressible inviscid flow through a linear cascade of arbitrary blade shapes. The method uses advanced surface singularity formulations which were adapted from those in current external flow analyses.
Mcfarland, E. R.
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Stabilizer bars: Part 2. Calculations - example

Transport Problems, 2011
The article contains the further outline of the calculation methods for stabilizer bars. Modern technological and structural solutions in contemporary cars are reflected also in the construction and manufacture of stabilizer bars. A proper construction and the selection of parameters influence the strength properties, the weight, durability and ...
Adam-Markus WITTEK, Hans-Christian RICHTER, Bogusław ŁAZARZ   +2 more
openaire   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Introducing elliptic, an R Package for Elliptic and Modular Functions [PDF]

This paper introduces the elliptic package of R routines, for numerical calculation of elliptic and related functions. Elliptic functions furnish interesting and instructive examples of many ideas of complex analysis, and the package illustrates these ...
Robin K. S. Hankin
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Analysis of Operating Conditions Pertaining to 3-Phase 4-Way Power Networks Using Statistical Method for Load Calculation

Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2011
The paper proposes a methodology for an analysis of phase-like load distribution and calculation of an optimum number of single electrical receivers per every phase of 3-phase 4-way power networks of 0.4/0.23 kV where a statistical method is used for ...
A. G. Arutiounian
doaj