Results 101 to 110 of about 12,609,494 (300)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
CALCULATION METHOD on limiting conditions OF PILES arranged USING bit-PULSE TECHNOLOGY
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019 An original calculation method of the CIT-piles on the bearing capacity and deformations in nonlinear-deformable earth foundation based on soil compaction in the discharge-pulse treatment zone is proposed.
V. E. Bykhoutsev +2 more
doaj
A steady-state target calculation method based on "point" model for integrating processes
, 2015 Aiming to eliminate the influences of model uncertainty on the steady-state target calculation for integrating processes, this paper presented an optimization method based on “point“ model and a method determining whether or not there is a ...
Pang Q(庞强) +3 more
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The calculation of noise from railway bridges and viaducts
, 2005 Pandrol Rail Fastenings Limited are a designer and manufacturer of railway rail-fastening systems. As an organisation they have the capability to reduce the noise impact of bridges using resilient track components. They also have a commercial interest in
Bewes, Oliver Guy
core +1 more source
Heart sound localization through non-linear time delay calculation method [PDF]
, 2007 This paper proposes a sound localization method for heart sounds recorded from subjects in normal noise environment. Various sound localization methods were investigated to discover a method suitable for heart sounds. Electronic stethoscopes were used to
Jahangir Bakhteri, Rabia Bakhteri
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source