Results 81 to 90 of about 566,577 (289)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The "Ridge" in Proton-Proton Scattering at 7 TeV

, 2011
One of the most important experimental results for proton-proton scattering at the LHC is the observation of a so-called "ridge" structure in the two particle correlation function versus the pseudorapidity difference $\Delta\eta$ and the azimuthal angle ...
Iu. Karpenko, K. Werner, P. Huovinen, T. Pierog   +3 more
core   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The chemical potential of a Lennard Jones fluid

, 2010
The aim of this paper is to present an analytical calculation of the chemical potential of a Lennard Jones fluid. The integration range is divided into two regions. In the small distance region,which is $r\leq\sigma$ in the usual notation,the integration
Celebonovic, V.
core   +3 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A nonequilibrium model for a moderate pressure hydrogen microwave discharge plasma [PDF]

This document describes a simple nonequilibrium energy exchange and chemical reaction model to be used in a computational fluid dynamics calculation for a hydrogen plasma excited by microwaves.
Scott, Carl D.
core   +1 more source

Hydrodynamic modeling of deconfinement phase transition in heavy-ion collisions at NICA-FAIR energies

, 2011
We use (3+1) dimensional ideal hydrodynamics to describe the space-time evolution of strongly interacting matter created in Au+Au and Pb+Pb collisions. The model is applied for the domain of bombarding energies 1-160 AGeV which includes future NICA and ...
A. S. Roshal, A. V. Merdeev, D. H. Rischke, I. N. Mishustin, I. N. Mishustin, I. N. Mishustin, I. N. Mishustin, L. D. Landau, L. D. Landau, L. D. Landau, L. M. Satarov, L. P. Csernai, Ya. B. Zeldovich   +12 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Application of flow and heat transfer network analysis method to the core of a prismatic gas-cooled micro reactor

Frontiers in Energy Research
The prismatic gas-cooled micro reactor core is composed of graphite prismatic blocks with gaps between them. The coolant passes through the gap to form flows that affect the flow and temperature distribution of the core.
Zhang Shuoting, Dong Jianhua, Zhou Zhe, Huang Zheng, Liu Guoming, Chen Qiaoyan   +5 more
doaj   +1 more source

A random walk model related to the clustering of membrane receptors

, 2012
In a cellular medium, the plasmic membrane is a place of interactions between the cell and its direct external environment. A classic model describes it as a fluid mosaic.
Lachal, Aimé
core   +2 more sources