Results 61 to 70 of about 835 (263)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The Cooperation Establishment Mechanism of EPC Project Consortium in Context of China: Form the Perspective of Trust

open access: yes, 2023
The purpose of this paper is to explore the establishment mechanism of an EPC consortium from the perspective of trust. Questionnaire surveys were undertaken to collect data from the experienced project managers of a design company group and a ...
Weiping Jiang, Shanqing Tang
core   +1 more source

AUTOMATIC BLOOD PRESSURE MEASUREMENT DEVICES FOR HOME USE – CAN WE TRUST THEM

open access: yesZdravniški Vestnik, 2009
Background This paper describes current state of evaluation of automatic BP devices in Slovenia and internationally. Conclusions In the last decades, non-invasive automatic blood pressure (BP) measurement devices are used with increasing regularity over ...
Gregor Geršak, Janko Drnovšek
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Analisis pengaruh hedonic dan utilitarian features, terhadap calculative commitment dan flow experience serta implikasinya terhadap e-loyalty : telaah pada pengguna website pegipegi.com [PDF]

open access: yes, 2017
Permintaan hotel pada jasa online booking terus mengalami peningkatan di setiap tahunnya untuk melengkapi travelling para konsumen terutama konsumen Gen Y.
Arlina, Sufi
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Survey on Trust Calculation Methods in Internet of Things

open access: yesProcedia Computer Science, 2019
Abstract The Internet of Things (IoT) is widely affecting our daily lives in many different activities and applications. IoT devices are ranging from a tiny wearable device to large industrial applications. Wide variety of IoT applications have been developed and deployed involving many devices and produced huge data.
Warsun Najib   +2 more
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Does Terrorism Dominate Citizens’ Hearts or Minds? The Relationship between Fear of Terrorism and Trust in Government

open access: yes, 2019
Terrorism only poses a small risk to people but tends to be a major source of public fear. Through fear, terrorism has far-reaching implications for public governance.
Kantorowicz, Jaroslaw   +7 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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