Results 221 to 230 of about 147,549 (388)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Spontaneous steinstrasse: A case report and literature review. [PDF]

open access: yesUrol Case Rep
Donega Yaméogo CAMK   +7 more
europepmc   +1 more source

Calculi for Synchrony and Asynchrony

open access: yesTheoretical Computer Science, 1983
R. Milner
semanticscholar   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Urinary calculi — atypical source of information on mercury in human biomonitoring

open access: yesOpen Chemistry, 2012
Kuta Jan   +4 more
doaj   +1 more source

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