Results 41 to 50 of about 49,947 (296)

Thoracolithiasis Mimicking a Pleural Plaque in a Patient with a History of Asbestos Exposure: A Case Report

open access: yes대한영상의학회지, 2017
A freely mobile calcified or noncalcified nodule in the pleural cavity, known as thoracolithiasis, is quite rare. There are several reports of CT findings of thoracolithiasis, but there is no report of thoracolithiasis mistakenly considered as a pleural
Yoon Ki Cha   +3 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

A middle aged women with bilateral staghorn complete calculi

open access: yesThe Pan African Medical Journal, 2014
A 50-year-old woman presented with a 2-years history of chronic flanc and hematuria. Plain abdominal radiography was performed showing bilateral complete staghorn calculi.
Jihad El Anzaoui, Driss Touiti
doaj   +1 more source

Pathogenesis and prevention of residual gall bladder: Report of three cases and review of literature

open access: yesArchives of Medicine and Health Sciences, 2014
Cholecystectomy is a common surgery performed for uncomplicated symptomatic gall stones as a definitive procedure. For complicated cases, partial or modified subtotal cholecystectomy has been described as an easy, safe, and definitive option.
Usha Dalal   +4 more
doaj   +1 more source

Association between interleukin-1 beta gene, interleukin-1 receptor antagonist gene polymorphisms and urolithiasis: A literature review and meta-analysis

open access: yesEuropean Journal of Inflammation, 2020
Several case-control studies have been performed in different populations to uncover the association between interleukin-1 beta gene, interleukin-1 receptor antagonist gene polymorphisms and urolithiasis.
Jiaxuan Qin, Jinchun Xing, Zonglong Cai
doaj   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

A vesicocutaneous fistula secondary to bladder calculi in a patient with spina bifida

open access: yesJournal of Surgical Case Reports, 2010
We present a rare case of a vesicocutaneous fistula secondary to two large bladder calculi in a patient with spina bifida. A 62 year old lady presented with swelling of her right thigh and a calcified mass protruding through the subcutaneous tissues of ...
Jonathan D Horsnell, Richard B Kinder
doaj  

Home - About - Disclaimer - Privacy