Results 71 to 80 of about 89,630 (300)

Silent But Giant: Giant ureteric calculus in a 7-year-old boy

Journal of Surgical Case Reports, 2010
Giant ureteric calculi are extremely rare in children. We present a case of a child who was originally admitted for observation following non-accidental injury and had an episode of painless haematuria as an inpatient.
D Mak, R Wragg, H Chandran, L McCarthy, K Parashar   +4 more
doaj  

A middle aged women with bilateral staghorn complete calculi

The Pan African Medical Journal, 2014
A 50-year-old woman presented with a 2-years history of chronic flanc and hematuria. Plain abdominal radiography was performed showing bilateral complete staghorn calculi.
Jihad El Anzaoui, Driss Touiti
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A termination proof of reduction in a simply typed calculus with constructors [PDF]

, 2011
The well-known proof of termination of reduction in simply typed calculi is adapted to a monomorphically typed lambda-calculus with case and constructors and recursive data types. The proof differs at several places from the standard proof. Perhaps it is
Sabel, David, Schmidt-Schauß, Manfred
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Methuosis Inducer SGI‐1027 Cooperates with Everolimus to Promote Apoptosis and Pyroptosis by Triggering Lysosomal Membrane Permeability in Renal Cancer

Advanced Science
The mTOR inhibitor everolimus has been approved as a sequential or second‐line therapy for renal cell carcinoma (RCC). However, the development of drug resistance limits its clinical applications.
Yu Luo, Bing Guan, Xiaoqi Deng, Peide Bai, Haichao Huang, Chaohao Miao, Anran Sun, Zhipeng Li, Dianqiang Yang, Xuegang Wang, Zhiqiang Shao, Yulong Wu, Jinchun Xing, Bin Chen, Tao Wang   +14 more
doaj   +1 more source

Gallstone ileus with a biliodigestive fistula

Journal of the Belgian Society of Radiology, 2013
Background: A 34-year-old woman with breast cancer, metastasized to bone and brain, was admitted to our hospital with abdominal discomfort, nausea and constipation. Physical examination revealed a diffuse tender abdomen without bowel sounds.
LJ Schijf, D Van der Vlies, AG Aalbers, A Bruining   +3 more
doaj   +1 more source

Logical Relations for Monadic Types

, 2008
Logical relations and their generalizations are a fundamental tool in proving properties of lambda-calculi, e.g., yielding sound principles for observational equivalence.
Abramsky, Adamek, Barr, Beck, DAVID NOWAK, Eilenberg, Fiore, Gierz, Gierz, Giry, Goubault-Larrecq, Goubault-Larrecq, Honsell, JEAN GOUBAULT-LARRECQ, Jung, Jung, Lazić, Ma, Mac Lane, Mitchell, Mitchell, Moggi, Pitts, Pitts, Plotkin, Plotkin, Reynolds, Stark, SŁAWOMIR LASOTA, Wadler, Zhang   +30 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source