Results 71 to 80 of about 57,059 (300)
Two loop detection mechanisms: a comparison [PDF]
, 1997 In order to compare two loop detection mechanisms we describe two calculi for theorem proving in intuitionistic propositional logic. We call them both MJ Hist, and distinguish between them by description as `Swiss' or `Scottish'. These calculi combine in
Howe, J. M. +3 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
BMC UrologyObjective To explore the clinical features of inflammatory myofibroblastic tumors (IMT) of the retroperitoneal and genitourinary system. Methods We conducted a retrospective analysis of the clinical data of 23 patients with pathologically confirmed ...
Qianhao Huang +7 more
doaj +1 more source
Contextual equivalence in lambda-calculi extended with letrec and with a parametric polymorphic type system [PDF]
, 2009 This paper describes a method to treat contextual equivalence in polymorphically typed lambda-calculi, and also how to transfer equivalences from the untyped versions of lambda-calculi to their typed variant, where our specific calculus has letrec ...
Sabel, David +2 more
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Cystinuria: Diagnosis, Medical and Surgical Management, and Emerging Therapies. A Narrative Review
Research and Reports in UrologyAlberto Zambudio Munuera,1,2 Patricia Rodriguez Parras,1,2 Juan Antonio Galan Llopis,3 Feliciano Grases Freixedas,4 Maria del Carmen Cano Garcia,1,2 Miguel Arrabal-Martin,1,2 Miguel Angel Arrabal Polo1,21Urology Department, San Cecilio University ...
Zambudio Munuera A +6 more
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source