Results 91 to 100 of about 751,666 (339)

New insights into Neolithic milk consumption through proteomic analysis of dental calculus

open access: yesArchaeological and Anthropological Sciences, 2019
There has long been debate over the origins of dairy consumption within European populations. Whilst it was previously assumed that lactase persistence (LP) was under positive selection following the advent of agriculture, recent genetic studies of ...
Sophy Charlton   +6 more
semanticscholar   +1 more source

At‐Home Early Diagnosis of Mastitis: Calibration‐Free Analysis of Sodium to Potassium Ratio in Breast Milk

open access: yesAdvanced Functional Materials, EarlyView.
MAMAWEL is introduced as the first calibration‐free potentiometric sensor for at‐home mastitis diagnosis. By measuring the sodium‐to‐potassium ratio in breast milk, the device reliably differentiates between healthy and mastitis‐affected samples with less than 10% error.
Ali Soleimani   +9 more
wiley   +1 more source

Free‐Form Microfluidic Microneedle Array Patches

open access: yesAdvanced Functional Materials, EarlyView.
Microfluidic microneedle array patches (MAPs) integrate hollow microneedles with embedded microfluidic channels, fabricated using high‐resolution 3D printing, to enable controlled transdermal delivery of liquid, mixed, or reconstituted therapeutics.
Ian A. Coates   +11 more
wiley   +1 more source

Naturally Derived Donor‐π‐Acceptor Compounds for Efficient Long‐Wavelength LEDs/Sunlight‐Induced Polymerization and High‐Precision Multiple 3D Printing

open access: yesAdvanced Functional Materials, EarlyView.
Two novel donor–π–acceptor photoinitiators enable ultrafast long‐wavelength photopolymerization under blue/green LEDs and sunlight. Effective at low intensities and concentrations, they overcome slow kinetics and permit rapid 3D printing via DLW, DLP, and LCD methods.
Ji Feng   +9 more
wiley   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

Biofluorescence imaging as a valid alternative for dental calculus detection

open access: yesPhotodiagnosis and Photodynamic Therapy
Background: Dental calculus is a major contributor to periodontal disease, and its effective removal depends on accurate detection. This study aimed to evaluate the detectability of dental calculus using quantitative biofluorescence imaging (BFI) and to ...
Sun-Young Lee   +4 more
doaj   +1 more source

Proteomic evidence of dietary sources in ancient dental calculus

open access: yesProceedings of the Royal Society B: Biological Sciences, 2018
Archaeological dental calculus has emerged as a rich source of ancient biomolecules, including proteins. Previous analyses of proteins extracted from ancient dental calculus revealed the presence of the dietary milk protein β-lactoglobulin, providing ...
Jessica Hendy   +19 more
semanticscholar   +1 more source

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang   +14 more
wiley   +1 more source

Differential preservation of endogenous human and microbial DNA in dental calculus and dentin

open access: yesScientific Reports, 2018
Dental calculus (calcified dental plaque) is prevalent in archaeological skeletal collections and is a rich source of oral microbiome and host-derived ancient biomolecules.
Allison E. Mann   +20 more
semanticscholar   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

open access: yesAdvanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter   +5 more
wiley   +1 more source

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