Results 191 to 200 of about 47,945 (344)

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Application of virtual reality haptic simulators in periodontics: insights from dental professionals. [PDF]

Front Oral Health
Arias-Herrera S, Catala-Oriola Z, Firmino-Canhoto J, Gramatges-Rojas A, Sittoni-Pino MF, Flacco N.   +5 more
europepmc   +1 more source

Tooth wear and dental calculus in a group of orca ( Orcinus orca ) stranded on the New Zealand southern coast

Carolina Loch, Ingrid N. Visser, Kali Stratford, Sophie White, Jon Wakefield, Steven D. Bull, Lydia Matenga, Muriel Johnstone, Ramari Oliphant Stewart   +8 more
openalex   +2 more sources

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

Control of Dental Calculus Prevents Severe Radiation-Induced Oral Mucositis in Patients Undergoing Radiotherapy for Nasopharyngeal Carcinoma

Yu Zeng, Yue Hu, Linjing Wang, Zhiwei Liao, Ming Jen Tan, Yanhao Kuang, Pan Gong, Bin Qi, Xin Zhen   +8 more
openalex   +1 more source

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

Oral health assessment in a prospective birth cohort study. [PDF]

BDJ Open
Kaan AM, Duijster DD, Ujcic-Voortman JK, Haring LV, Volgenant CMC, Zaura E.   +5 more
europepmc   +1 more source

Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity

Advanced Science, EarlyView.
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee, Minjae Kim, Gha Yeon Park, Jubeen Yoon, Kunyoo Shin, Chang Ho Sohn, Myunghwan Choi   +6 more
wiley   +1 more source

MCV/Q, Medical College of Virginia Quarterly, Vol. 14 No. 4 [PDF]

, 1978

core   +1 more source

Neanderthal medics? Evidence for food, cooking, and medicinal plants entrapped in dental calculus

, 2012
Karen Hardy, Stephen Buckley, Matthew J. Collins, Almudena Estalrrich, Don Brothwell, Les Copeland, Antonio García‐Tabernero, Samuel García‐Vargas, Marco de la Rasilla Vives, Carles Lalueza‐Fox, Rosa Huguet, Markus Bastir, David Santamaría Álvarez, Marco de la Rasilla Vives, Julie Wilson, Ángel Fernández‐Cortés, Antonio Rosas   +16 more
openalex   +1 more source