Results 241 to 250 of about 47,126 (303)

Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting SPP1‐mediated macrophage polarization via the PI3K/Akt pathway

Animal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang, Tian Li, Weiran Jia, Dingjie Xu, Liangdan Sun, Yanlei Ge, Yiwei Shi, Hong Xu, Xudong Song, Fuyu Jin, Na Mao   +10 more
wiley   +1 more source

FDA-Approved AI Solutions in Dental Imaging: A Narrative Review of Applications, Evidence, and Outlook. [PDF]

Int Dent J
Shujaat S, Aljadaan H, Alrashid H, Aboalela AA, Riaz M.   +4 more
europepmc   +1 more source

Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1‐mediated P53 ubiquitination

Animal Models and Experimental Medicine, EarlyView.
Based on a dermis fibroblast Gorab knockout mouse model, this study revealed that Gorab deficiency promotes skin aging by influencing RCHY1, causing a decrease in P53 ubiquitination, damaging the activity of HDAC2, further resulting in the accumulation of aging‐related proteins (P53, P21, P16) and a reduction in extracellular matrix (ECM) components ...
Yanhong Li, Wei Liang, Yanfeng Xu, Yunlin Han, Wenjie Zhao, Siyuan Wang, Wei Deng, Chuan Qin   +7 more
wiley   +1 more source

A preliminary study on oral health status and unmet dental needs in patients with home-based psychiatric services. [PDF]

Sci Rep
Suga T, Tu TTH, Gamo Y, Asakura T, Iida S, Iwase Y, Toyofuku A.   +6 more
europepmc   +1 more source

Establishment of a mouse model of propylthiouracil‐induced antineutrophil cytoplasmic antibody‐associated vasculitis

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract summarizes our study in which we established a novel murine model of antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis. Neutrophil recruitment was induced using thioglycolate, followed by timed administration of propylthiouracil and phorbol 12‐myristate 13‐acetate to generate DNase I‐resistant neutrophil ...
Sakiko Masuda, Momo Uchizawa, Chihiro Terasaka, Takumi Abe, Tetsuro Nakamura, Yuka Nishibata, Yusho Ueda, Daigo Nakazawa, Utano Tomaru, Akihiro Ishizu   +9 more
wiley   +1 more source

Florida probe combined with guided biofilm therapy in the treatment of severe periodontitis: a case report. [PDF]

BMC Oral Health
Zhu Q, Sun F, Fan Y, Wang P, Yang Y.
europepmc   +1 more source

Host Traits Impact the Outcome of Metagenomic Library Preparation From Dental Calculus Samples Across Diverse Mammals. [PDF]

Mol Ecol Resour
Moraitou M, Richards JL, Bolyos C, Saliari K, Gilissen E, Timmons Z, Kitchener AC, Pauwels OSG, Sabin R, Kokkini P, Portela Miguez R, Guschanski K.   +11 more
europepmc   +1 more source

Wet Lab Protocols Matter: Choice of DNA Extraction and Library Preparation Protocols Bias Ancient Oral Microbiome Recovery. [PDF]

Mol Ecol Resour
Wright SL, Abdul-Aziz M, Blaha GN, Ta CK, Gancz A, Ademola-Popoola IJ, Szécsényi-Nagy A, Sereno PC, Weyrich LS.   +8 more
europepmc   +1 more source

Prevalence and Socio-Behavioural Determinants of Periodontal Disease Among Adults in the Northern West Bank: A Cross-Sectional Study. [PDF]

Dent J (Basel)
Al-Hassan S, Kazlak M, Kateeb E.
europepmc   +1 more source