Results 131 to 140 of about 377,226 (300)

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

Advanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao, Linlin Sheng, Jianhao Qiu, Junjie Ma, Kai Jin, Binggong Zhao, Tianrun Miao, Jing Chen, Yehong Li, Zhan Zhang, Dongfeng Sun, Yongmeng Li, Hui Tian   +12 more
wiley   +1 more source

Review: Opportunities and challenges for the genetic selection of dairy calf disease traits

Animal
Interest in dairy cow health continues to grow as we better understand health’s relationship with production potential and animal welfare. Over the past decade, efforts have been made to incorporate health traits into national genetic evaluations ...
C. Lynch, E.M. Leishman, F. Miglior, D. Kelton, F.S. Schenkel, C.F. Baes   +5 more
doaj   +1 more source

Labour efficiency on-farm [PDF]

, 2007
End of project reportImprovements in milking efficiency have a greater influence than any other aspect of the dairy farmers work on overall farm labour inputs (Whipp, 1992).
Boyle, Laura, Gleeson, David E, Kinsella, J., McNamara, John G., Mee, John F, O'Brien, Bernadette, O'Donovan, K., Ruane, D.   +7 more
core  

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

Improving beef calf health: frequency of disease syndromes, uptake of management practices following calving, and potential for antimicrobial use reduction in western Canadian herds. [PDF]

Transl Anim Sci, 2022
Waldner C, Wilhelm B, Windeyer MC, Parker S, Campbell J.   +4 more
europepmc   +1 more source

Thermal Cyclotrimerization Bridges Polymer‐Filler Interfaces for High‐Performance CO2 Separation Membranes

Advanced Science, EarlyView.
Thermal cyclotrimerization of nitriles converts interfacial discontinuity in MAF‐stu‐1/PIM‐1 MMMs into a continuity‐enhanced junction. Triazine–Zn2+ coordination between TR‐PIM chains and MAF‐stu‐1, together with hydrogen bonding and π–π stacking, lowers interfacial tension and builds selective CO2 pathways, enabling > 10 000 barrer CO2 permeability ...
Zhihong Lin, Kaifang Wang, Ziyi Yuan, Jiali Tang, Xiaozhen Liu, Liu Chen, Lu Shao, Xuezhong He   +7 more
wiley   +1 more source

Improving dairy calf health through inclusion of diarrhea and respiratory health data into a US national genetic evaluation

Journal of Dairy Science
: Calf diarrhea (DIAR) and respiratory illnesses (RESP) are leading causes of calf mortality. This study aimed to develop a comprehensive US national genomic evaluation for these important calf health traits using producer-recorded data from the National
Mahesh Neupane, Kristen L. Parker Gaddis, Sajjad Toghiani, Asha M. Miles, Jason R. Graham, Javier F. Burchard, João W. Dürr, John B. Cole, Jeffrey R. O'Connell, Curtis P. Van Tassell, Paul M. VanRaden   +10 more
doaj   +1 more source

A comparison of indoor and outdoor calf housing systems using automated and manual feeding methods and their effect on calf health, behavior, growth, and labor. [PDF]

J Anim Sci, 2022
Sinnott AM, Bokkers EAM, Murphy JP, Kennedy E.   +3 more
europepmc   +1 more source

Impact of different handling styles (good vs. adverse) on growth performance, behavior, and cortisol concentrations in beef cattle [PDF]

, 2012
Our objective was to determine effects of aggressive handling on growth performance, behavior, and cortisol concentrations in beef calves. Crossbred calves (313 ± 4.7 kg; n = 54; 24 steers, 30 heifers) from a single herd were stratified by gender, body ...
Bauer, Joan, Galloway, Doug, Hornsby, J. A. (Pete), Kegley, Beth, Reynolds, Jana, Richeson, John   +5 more
core   +2 more sources

A Fully Self‐Powered Digital Wearable System for the Auxiliary Treatment of Plantar Fasciitis

Advanced Science, EarlyView.
This study reports a system‐level fully self‐powered digital wearable system (FS‐DWS) for the auxiliary treatment of plantar fasciitis. By integrating arch support, energy harvesting, wearable sensing, and machine learning‐driven closed‐loop visualized feedback, the system enables effective plantar pressure reduction and self‐powered, real‐time plantar
Jiacheng Hou, Ying Hong, Shiyuan Liu, Qiqi Pan, Jingyu Zhang, Qingyang Xu, Qiyi Nie, Zhonghe Wang, Liming Xin, Yilong Wang, Biao Wang   +10 more
wiley   +1 more source