Results 211 to 220 of about 12,020,800 (260)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Strain Rate Angle Distribution as an Indicator of Post‐Infarct Myocardial Remodeling: Proof‐of‐Concept of a Novel Application of the MRI Derived Strain Rate Tensor Field

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Left ventricular (LV) strain is an early indicator of myocardial dysfunction. However, conventional strain metrics do not fully account for the multidirectional nature of myocardial deformation. The strain rate tensor, derived from velocity‐encoded MRI, represents the time‐resolved magnitude and direction of strain rate without the ...
Lasse Totland   +7 more
wiley   +1 more source

An Adaptive Metasurface for Adjustable Magnetic Resonance Imaging Enhancement at 3 T and 7 T: A Feasibility Study

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Ultra‐high field (≥ 7 T) and 3 T MRI suffer from B1+ inhomogeneity and signal loss. Conventional metasurfaces that mitigate B1+ inhomogeneity and improve image SNR are “fixed” in nature and designed for a single Larmor frequency. This study demonstrates the feasibility of an adaptive metasurface utilizing voltage‐controlled capacitors ...
Paul S. Jacobs   +7 more
wiley   +1 more source

Using High‐Field Magnetic Resonance Spectroscopy to Measure Muscle Glycogen in Patients With McArdle Disease

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Patients with McArdle disease demonstrate exercise intolerance with muscle contractures and episodic rhabdomyolysis. Additionally, some patients show progressive fat replacement of paraspinal and shoulder muscles with aging.
Mads Godtfeldt Stemmerik   +4 more
wiley   +1 more source

Urinary Incontinence and Risk of All‐Cause Mortality: A Systematic Review and Meta‐Analysis of Observational Studies

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims Urinary incontinence (UI) is a prevalent condition among adults and imposes a substantial societal burden, yet its association with all‐cause mortality remains uncertain. This study systematically reviewed and quantified the association between UI and mortality risk.
Yanyan Zhou   +6 more
wiley   +1 more source

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