Results 31 to 40 of about 12,020,800 (260)

Bulk tank milk ELISA as screening test for Mycoplasma bovis: herd classification based on serology and PCR testing of different age groups

open access: yesIrish Veterinary Journal
Herd-level infection status for Mycoplasma bovis is commonly assessed by detecting antibodies in bulk tank milk (BTM) samples. However, the association between BTM serology and active circulation of the pathogen at farm level remains largely unclear, in ...
Jolien Vandewalle   +5 more
doaj   +1 more source

Health indicators in surplus calves at the time of arrival at auction markets: Associations with distance from farms of origin in Québec, Canada

open access: yesJournal of Dairy Science, 2023
: This study evaluated the associations between estimated distance from farms' locations to auction markets, and health indicators of surplus dairy calves sold during summer 2019 and winter 2020 in Québec, Canada.
Jean Silva Ramos   +10 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Effects of weaning strategies on health, hematology, and productivity in Holstein dairy calves

open access: yesJournal of Dairy Science, 2023
: Weaning strategies in dairy calves vary considerably, though the effect on animal health is unclear. This study examined the effects of calf weaning age (6 vs. 8 wk) and pace (abrupt vs.
A.R. Wolfe   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Genetic variation in novel calf traits using a farmer-centered, co-design approach to data collection

open access: yesJournal of Dairy Science
: Improving calf health on dairy farms contributes to animal welfare and business productivity gains. In recent years, traditional genetic evaluations have broadened to include cow health traits that have economic importance.
M.M. Axford   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The effect of bovine leukemia virus infection on health and growth of nonreplacement dairy calves

open access: yesJournal of Dairy Science
: The objective of this cohort study was to determine if bovine leukemia virus (BLV) positivity, identified using quantitative PCR (qPCR), was associated with health and growth outcomes in nonreplacement dairy calves.
K. Broadfoot   +5 more
doaj   +1 more source

Mastitis incidence and milk quality in organic dairy farms which use suckling systems in calf rearing [PDF]

open access: yes, 2008
In order to identify important factors influencing animal health and general disease resistance, detailed qualitative and quantitative farm data were collected from 99 organic dairy farms in the Netherlands. Mastitis incidence and milk quality were focal
Smolders, E.A.A.   +2 more
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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