Advanced Materials, EarlyView.A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton +17 more
wiley +1 more source
External validation, recalibration, and clinical utility of the kidney failure risk equation in patients with advanced CKD: a nationwide retrospective cohort analysis in Peru. [PDF]
BMC NephrolBravo-Zúñiga JI +7 more
europepmc +1 more source
Toward Energy Efficient Electrochemical Valorization of Waste Nitrate and Sulfide
Advanced Materials, EarlyView.This work introduces an integrated electrochemical strategy couples nitrate reduction with sulfide oxidation for energy‐efficient wastewater valorization. A Cu‐Co dual‑site catalyst, engineered for close proximity, promotes *NO2 relay and subsequently NH3 formation, enabling the system to operate at substantially reduced cell voltages and produce high ...
Bihao Hu +5 more
wiley +1 more source
Influencing factor analysis and prediction model construction of dupilumab treatment adherence: a prospective cohort study in moderate-to-severe atopic dermatitis. [PDF]
Front ImmunolOuyang P +5 more
europepmc +1 more source
Advanced Materials, EarlyView.Residual magnetization induces pronounced mechanical anisotropy in ultra‐soft magnetorheological elastomers, shaping deformation and actuation even without external magnetic fields. This study introduces a computational‐experimental framework integrating magneto‐mechanical coupling into topology optimization for designing soft magnetic actuators with ...
Carlos Perez‐Garcia +3 more
wiley +1 more source
Benchmarking survival machine learning models for 10-year cardiovascular disease risk prediction using large-scale electronic health records. [PDF]
Digit HealthLiu T, Krentz A, Lu L, Wang Y, Curcin V.
europepmc +1 more source
Navigating Ternary Doping in Li‐ion Cathodes With Closed‐Loop Multi‐Objective Bayesian Optimization
Advanced Materials, EarlyView.The search for advanced battery materials is pushing us into highly complex composition spaces. Here, a space with about 14 million unique combinations is efficiently explored using high‐throughput experimentation guided by Bayesian optimization with a deep kernel trained on both the Materials Project database and our data.
Nooshin Zeinali Galabi +6 more
wiley +1 more source
Analysis of risk factors for adverse outcomes and development of a predictive model in patients with acute mild ischemic stroke following intravenous thrombolytic therapy with rt-PA. [PDF]
BMC NeurolXiao Y +8 more
europepmc +1 more source
Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities
Advanced Materials, EarlyView.As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas +7 more
wiley +1 more source
Cardiovascular disease risk prediction in multi-ethnic Asian populations: evidence from two population-based cohorts in Singapore. [PDF]
Lancet Reg Health West PacLim CGY +13 more
europepmc +1 more source