Results 61 to 70 of about 485,703 (257)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

The First LWA Swarm Calibrator Survey

The Astrophysical Journal
The LWA Swarm is an aperture synthesis telescope consisting of interconnected Long Wavelength Array (LWA) stations autonomously making joint observations.
C. A. Taylor, G. B. Taylor, J. Dowell, S. Pezzaioli   +3 more
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

The Impact of Beam Variations on Power Spectrum Estimation for 21 cm Cosmology. II. Mitigation of Foreground Systematics for HERA

The Astrophysical Journal, 2023
One key challenge in detecting a 21 cm cosmological signal at z > 6 is to separate the cosmological signal from foreground emission. This can be studied in a power spectrum space where the foreground is confined to low delay (or, equivalently, k _ ...
Honggeun Kim, Nicholas S. Kern, Jacqueline N. Hewitt, Bang D. Nhan, Joshua S. Dillon, Eloy de Lera Acedo, Scott B. C. Dynes, Nivedita Mahesh, Nicolas Fagnoni, David R. DeBoer   +9 more
doaj   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Improved Method for GLONASS Long Baseline Ambiguity Resolution without Inter-Frequency Code Bias Calibration

Remote Sensing, 2018
Use of a frequency-division multiple access strategy causes Globalnaya Navigatsionnaya Sputnikovaya Sistema (GLONASS) receiving equipment to experience both inter-frequency phase bias (IFPB) and inter-frequency code bias (IFCB).
Jiasong Zhu, Yanyan Liu, Bing Wang, Shirong Ye   +3 more
doaj   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Nomogram to predict survival of patients with advanced and metastatic pancreatic Cancer

BMC Cancer, 2021
Background Nomograms are rarely employed to estimate the survival of patients with advanced and metastatic pancreatic cancer (PC). Herein, we developed a comprehensive approach to using a nomogram to predict survival probability in patients with advanced
G. C. Deng, Y. Lv, H. Yan, D. C. Sun, T. T. Qu, Y. T. Pan, Q. L. Han, G. H. Dai   +7 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Modeling Atmospheric Phase Corruptions in High-frequency Very-long-baseline Interferometry Using Gaussian Processes

The Astronomical Journal
Using very-long-baseline interferometry (VLBI) observations at (sub)millimeter wavelengths, the Event Horizon Telescope (EHT) currently achieves the finest angular resolution of any astronomical facility, necessary for imaging the horizon-scale structure
Uri Rolls, Dominic W. Pesce, Paul Tiede, Lindy Blackburn, Iniyan Natarajan, Sheperd S. Doeleman   +5 more
doaj   +1 more source