Results 71 to 80 of about 619,717 (297)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Some Calibration Estimators of the Mean of a Sensitive Variable Under Measurement Error

Mathematics
This study explores the estimation of the mean of a sensitive variable using calibration estimators under measurement error. Three randomized response techniques are evaluated: Partial Randomized Response Technique, Compulsory Randomized Response ...
Sat Gupta, Pidugu Trisandhya, Frank Coolen   +2 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Scheffé-type Confidence Region for the Calibration Line

Austrian Journal of Statistics, 2016
Analyzed is the comparative calibration problem in the case when linear relationship is assumed between two considered measuring devices. The method deriving the approximate confidence region for the unknown parameters of the calibration line based on ...
Gejza Wimmer, Viktor Witkovský
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Pointwise universal consistency of nonparametric linear estimators [PDF]

, 2004
This paper presents sufficient conditions for pointwise universal consistency of nonparametric delta estimators.
Vidal-Sanz, José M.
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

The Performance of Multivariate Calibration on Ratios, Means and Proportions

Revista Colombiana de Estadística, 2016
In this paper, the calibration approach is revisited in order to allow new calibration weights that are subject to the restriction of multiple calibration equations on a vector of ratios, means and proportions.
HUGO ANDRÉS GUTIÉRREZ ROJAS, HANWEN ZHANG, NELSON ANDRÉS RODRÍGUEZ   +2 more
doaj   +1 more source

Calibration estimator for Head Count Index

International Journal of Computer Mathematics, 2018
This paper considers the problem of estimating a poverty measure, the Head Count Index, using the auxiliary information available, which is incorporated into the estimationprocedure by calibration techniques. The proposed method does not directly use the auxiliary information provided by auxiliary variables related to the variable of interest in the ...
Martínez, Sergio, Illescas, María Dolores, Martínez, Helena, Arcos, Antonio   +3 more
openaire   +4 more sources