Results 61 to 70 of about 3,069,221 (295)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Enhancing Spectroscopic Experiment Calibration through Differentiable Programming

Condensed Matter
In this work, we present an innovative calibration technique leveraging differentiable programming to enhance energy resolution and reduce the energy scale systematic uncertainty in X-ray spectroscopic experiments.
Fabrizio Napolitano
doaj   +1 more source

A Study for Efficient Methods of System Calibration between Optical and Range Sensors [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
Recently, interests in 3D indoor modeling and positioning have been growing. Data fusion by using different sensors data is one of the 3D model producing methods. For a data fusion between two kinds of sensors, precise system calibration is essential. If
W. Choi, C. Kim, Y. Kim
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Space Layer Experiment (SLX) Sensor Calibration [PDF]

, 2014
The space layer experiment (SLX) is a sensor planned by the US Missile Defense Agency (MDA) to test technology to observe and track objects in space. Subject to SLX program and funding restraints, a detailed and thorough ground calibration is planned to ...
Zollinger, Lorin, Thompson, Brian, Kantsiper, Brian, Wada, Dean, Hawkins, Ed, Hansen, Scott   +5 more
core   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

PointQ model of an arterial network: calibration and experiments

CoRR, 2015
The calibration of a PointQ arterial microsimulation model is formulated as a quadratic programming problem (QP) whose decision variables are link flows, demands at entry links, and turn movements at intersections, subject to linear constraints imposed by flow conservation identities and field measurements of a subset of link flows (counts), demands ...
Lioris, Jennie, Muralidharan, Ajith, Gouy, Martin, Varaiya, Pravin, YILDIZ TAŞCIKARAOĞLU, Fatma   +4 more
openaire   +4 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging.

PLoS ONE, 2016
Due to low fluorine background signal in vivo, 19F is a good marker to study the fate of exogenous molecules by magnetic resonance imaging (MRI) using equilibrium nuclear spin polarization schemes.
Alexander J Taylor, Josef Granwehr, Clémentine Lesbats, James L Krupa, Joseph S Six, Galina E Pavlovskaya, Neil R Thomas, Dorothee P Auer, Thomas Meersmann, Henryk M Faas   +9 more
doaj   +1 more source

Concept for improved radiometric calibration of radiance sources at the CHB facility [PDF]

, 2010
The Calibation Home Base (CHB) is a facility for the calibration of airborne imaging spectrometers such as APEX, ROSIS and in the future ARES, and for field spectrometers. Absolute radiometric calibration in the spectral range of 350–2500 nm is currently
Schötz, Paul, Fries, Jochen, Gege, Peter, Haschberger, Peter, Lenhard, Karim, Schwarz, Christian, Schwarzmaier, Thomas   +6 more
core