Results 51 to 60 of about 4,972 (174)
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency, characterised by impaired antibody production, immune dysregulation, and a broad spectrum of clinical manifestations. Gastrointestinal involvement is frequent, affecting up to 20% of patients and significantly contributing to morbidity and ...
Györgyi Műzes, Ferenc Sipos
wiley +1 more source
Intercellular Transmission of Naked Viruses through Extracellular Vesicles: Focus on Polyomaviruses
Extracellular vesicles have recently emerged as a novel mode of viral transmission exploited by naked viruses to exit host cells through a nonlytic pathway.
Francois Helle +4 more
doaj +1 more source
RNA viruses causing human diseases impinge public health and the worldwide economy, as are the case of the current SARS-CoV-2 pandemic. These infectious pathogens are well known to control cellular machinery to complete their replication cycle ...
Magda E. Vera-Garcia +8 more
doaj +1 more source
Prevalence and Genotype Distribution of Sapovirus in China: A Systematic Review and Meta‐Analysis
This review highlights a distinct age‐related trend in Sapovirus (SaV) prevalence in China, peaking among kindergarten children and adults. These results not only enhance the understanding of SaV's epidemiology but also provide a robust foundation for estimating disease burden and informing the development of targeted vaccines and public health ...
Zhao Gao +6 more
wiley +1 more source
Identification of a Novel Calicivirus in Walrus ( Odobenus Rosmarus )
Caliciviruses are associated with several disease symptoms, such as diarrhea, respiratory infections, vesicular lesions, reproductive failure, and fatal hemorrhagic disease in animals.
Yi Huang +13 more
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Cell Cycle Arrest is a Conserved Function of Norovirus VPg Proteins
Murine norovirus (MNV) viral protein genome-linked (VPg) manipulates the cell cycle to induce a G0/G1 arrest and gain a beneficial replication environment.
Alice McSweeney +2 more
doaj +1 more source
Comparative analysis of the extent of protein–protein interactions in icosahedral viral capsids
Abstract Nonenveloped viruses package, carry, and deliver their genomes to the targeted cells using protein shells known as capsids. The viral capsids come in different shapes and sizes, most exhibiting helical or icosahedral symmetries. Here, we analyzed 634 icosahedral capsids at high resolution (<4 Å) from 39 virus families with T‐numbers ranging ...
Noah J. Zimmerman +2 more
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Synthesis and Antiviral Activity of Bis-Histidyl Diaminoalkanes in Relation to Feline calicivirus
An RNA-containing virus of the Vesivirus genus Caliciviridae family causes feline calicivirosis, a disease widely spread worldwide. The literature describes a systemic form of infection leading to the death of up to 60% of sick animals (FCV-VSD).
L. S. Koroleva +5 more
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Differential Viral Genome Diversity of Healthy and RSS-Affected Broiler Flocks
The intestinal virus community contributes to health and disease. Runting and stunting syndrome (RSS) is associated with enteric viruses and leads to economic losses in the poultry industry. However, many viruses that potentially cause this syndrome have
Jakub Kubacki +2 more
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Diagnostic electron microscopy in human infectious diseases – Methods and applications
Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley +1 more source

