A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
Design and strength analysis of a test bench for brake calipers on suspended monorail trains
Brake calipers serve as the actuators in braking systems and are critical components for ensuring the safe operation of trains. However, there is currently a lack of dedicated test benches for brake calipers used on suspended monorail trains that employ ...
JIANG Yongzhi +4 more
doaj
Differences between Four Skinfold Calipers in the Assessment of Adipose Tissue in Young Adult Healthy Population [PDF]
Francisco Esparza-Ros +5 more
openalex +1 more source
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi +7 more
wiley +1 more source
Modeling the Error of Caliper Measurements in Animal Experiments
Cancer prevention and treatment is one of the most significant public health challenges of the 21st century. Cancer is a serious health problem, and it is the second leading cause of death following cardiovascular diseases.
Melania Puskas, Daniel Andras Drexler
doaj +1 more source
Measurement of dimensions and alignment with optical instruments [PDF]
Course, as contained in manual, encompasses principles involved in determining and applying proper optical tooling devices to fulfill precise measuring ...
Dendy, W. F.
core +1 more source
Cold Quad‐Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking
Multimodal albumin–bismuth sulfide–superparamagnetic iron oxide (ABS) nanocomplexes are developed for stem cell tracking across four different imaging modalities: MRI, MPI, MSOT, and CT. Combining its flexibility with high sensitivity, this quad‐modal imaging agent enables a robust quantification of ABS‐labeled stem cells in vivo.
Ali Shakeri‐Zadeh +4 more
wiley +1 more source
Effect of Optical Coating and Surface Treatments on Mechanical Loss in Fused Silica
We report on the mechanical loss in fused silica samples with various surface treatments and compare them with samples having an optical coating. Mild surface treatments such as washing in detergent or acetone were not found to affect the mechanical loss
Gretarsson, Andri M. +5 more
core +3 more sources
Counterion Dependent Side‐Chain Relaxation Stiffens a Chemically Doped Thienothiophene Copolymer
Oxidation of a thienothiophene copolymer, p(g3TT‐T2), via different doping strategies and dopant molecules resulted in materials with similar oxidation levels and a high electrical conductivity of ≈100 S cm−1. However, mechanical properties varied significantly, with sub‐glass transition temperatures and elastic moduli spanning from –44°C to –3°C and ...
Mariavittoria Craighero +12 more
wiley +1 more source
Guadecitabine, in combination with Cyclophosphamide, promotes anti- cancer immunity in BALB/c mice bearing 4T1 mouse mammary carcinoma [PDF]
Background: The extremely high mortality rate of patients diagnosed with triple negative breast cancer makes it one of the deadliest forms of cancer. Due to the heterogenous nature of tumors, complete clearance is not achieved and clonal selection occurs
Bear MD, Harry D. +3 more
core +1 more source

