Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis
Advanced Science, EarlyView.Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang +7 more
wiley +1 more source
Polyp-Size: A Precise Endoscopic Dataset for AI-Driven Polyp Sizing
Scientific DataColorectal cancer often arises from precancerous polyps, where accurate size assessment is vital for clinical decisions but challenged by subjective methods.
Yiming Song +13 more
doaj +1 more source
EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer
Advanced Science, EarlyView.This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv +8 more
wiley +1 more source
Ciência Animal Brasileira, 2008 <span><p align="justify">Biometric testicular traits were evaluated on 24 entire male Santa Inês lambs, with mean initial weight of 24.5 kg ± 2.88.
Helder Louvandini +4 more
doaj
The management of patients with injury of the cervical spine using blackburn skull calipers and the stryker turning frame [PDF]
, 1965 Phillip Harris, Peter H T Wu
openalex +1 more source
An Assessment of the Accuracy of Recurring Esthetic Dental Proportion: An In Vivo Comparative Analysis of Maxillary Anterior Teeth Proportion With Chu’s Gauge and Custom-Made Calipers [PDF]
, 2023 Prakyath Malli +5 more
openalex +1 more source
Advanced Science, EarlyView.This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
A Degradable Bioinspired Flier with Aerogel‐Based Colorimetric Sensors for Environmental Monitoring
Advanced Science, EarlyView.Biodegradable fliers are developed inspired by Tipuana tipu samaras, integrating cellulose nanocrystal aerogel (CNCa) sensors loaded with natural dyes for pH and ammonia detection. The lightweight, degradable fliers mimic natural morphology and aerodynamics, offering an eco‐friendly, scalable solution for in situ environmental monitoring after passive ...
Gianpaolo Gallo +4 more
wiley +1 more source
Mapping the Structural Dynamics Within the Shaker Potassium Channel using Tethered Spectroscopic Probes as Chemical Calipers [PDF]
, 2012 Brian W. Jarecki +6 more
openalex +1 more source