Amplifying Anti‐Tumor Immune Responses via Mitochondria‐Targeting Near‐Infrared Photodynamic Therapy
Interfacial Nd3+‐triplet energy transfer enables direct activation of molecular triplets under near‐infrared (NIR) irradiation for reactive oxygen species (ROS) generation. Photodynamic therapy (PDT) exaggerates hypoxia, which initiates subsequent hypoxia‐activated chemotherapy.
Cheng‐Ao Li+13 more
wiley +1 more source
Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer. [PDF]
Jeong H+15 more
europepmc +1 more source
This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding+16 more
wiley +1 more source
Research on variable-length control chart pattern recognition based on sliding window method and SECNN-BiLSTM. [PDF]
Zan T+5 more
europepmc +1 more source
EGFR‐TKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer
Drug‐tolerant persister (DTP) cells emerge early during EGFR‐TKI treatment, preceding the development of acquired resistance. Elevated DPP4 in DTP cells drives metabolic reprogramming and antioxidant adaptation, promoting cell survival under drug pressure.
Yuanzhou Zhang+7 more
wiley +1 more source
Cadaveric Case Report of Pelvic and Abdominal Anatomy in an Individual With a Müllerian Duct Anomaly. [PDF]
Lane F+5 more
europepmc +1 more source
ABSTRACT Smallholder agriculture remains a cornerstone for economic development and poverty reduction in Latin America. Their transition to sustainable agricultural production is critical in the face of the environmental challenges posed by conventional farming practices and is a key pathway to achieving the United Nations' Sustainable Development ...
Gabriela Carbajo‐Alvarez+2 more
wiley +1 more source
Comparing the Efficiency of Fluid Infusion Systems for Pars Plana Vitrectomy. [PDF]
Rossi T+7 more
europepmc +1 more source
Overall survival of patients who underwent surgical resection was significantly better compared to that of patients who underwent chemotherapy without surgical resection. These results highlight the benefit of surgical intervention to survival for patients with isolated para‐aortic lymph node metastasis or with resectable liver metastasis.
Akira Ouchi+39 more
wiley +1 more source
Persistent articular infection and host reactive response contribute to <i>Brucella</i>-induced spondyloarthritis in SKG mice. [PDF]
Harms JS+4 more
europepmc +1 more source