Results 221 to 230 of about 76,600 (323)

Amplifying Anti‐Tumor Immune Responses via Mitochondria‐Targeting Near‐Infrared Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
Interfacial Nd3+‐triplet energy transfer enables direct activation of molecular triplets under near‐infrared (NIR) irradiation for reactive oxygen species (ROS) generation. Photodynamic therapy (PDT) exaggerates hypoxia, which initiates subsequent hypoxia‐activated chemotherapy.
Cheng‐Ao Li   +13 more
wiley   +1 more source

Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer. [PDF]

open access: yesJ Immunother Cancer
Jeong H   +15 more
europepmc   +1 more source

ASO Therapy Targeting STAU2 to Inhibit Pancreatic Ductal Adenocarcinoma Progression and Metastasis by Regulating the PALLD‐Mediated EMT Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding   +16 more
wiley   +1 more source

EGFR‐TKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer

open access: yesAdvanced Science, EarlyView.
Drug‐tolerant persister (DTP) cells emerge early during EGFR‐TKI treatment, preceding the development of acquired resistance. Elevated DPP4 in DTP cells drives metabolic reprogramming and antioxidant adaptation, promoting cell survival under drug pressure.
Yuanzhou Zhang   +7 more
wiley   +1 more source

Do Sustainable Agricultural Practices Boost Production and Technical Efficiency? A Case Study of Coffee Smallholders in Peru

open access: yesAgribusiness, EarlyView.
ABSTRACT Smallholder agriculture remains a cornerstone for economic development and poverty reduction in Latin America. Their transition to sustainable agricultural production is critical in the face of the environmental challenges posed by conventional farming practices and is a key pathway to achieving the United Nations' Sustainable Development ...
Gabriela Carbajo‐Alvarez   +2 more
wiley   +1 more source

Comparing the Efficiency of Fluid Infusion Systems for Pars Plana Vitrectomy. [PDF]

open access: yesTransl Vis Sci Technol
Rossi T   +7 more
europepmc   +1 more source

Does surgical intervention contribute to survival for patients with para‐aortic lymph node metastasis from colorectal cancer?

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Overall survival of patients who underwent surgical resection was significantly better compared to that of patients who underwent chemotherapy without surgical resection. These results highlight the benefit of surgical intervention to survival for patients with isolated para‐aortic lymph node metastasis or with resectable liver metastasis.
Akira Ouchi   +39 more
wiley   +1 more source

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