Results 141 to 150 of about 358,887 (259)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A Retrospective Analysis of Jordan's National COVID-19 Call Center: Operations, Effectiveness, and Lessons Learned. [PDF]

J Multidiscip Healthc
Alrawashdeh A, Simmons N, Alhawarat M, Maayeh MS, Kheirallah KA.   +4 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Leveraging Large Language Models for Improved Understanding of Communications With Patients With Cancer in a Call Center Setting: Proof-of-Concept Study. [PDF]

J Med Internet Res
Cho S, Lee M, Yu J, Yoon J, Choi JB, Jung KH, Cho J.   +6 more
europepmc   +1 more source

Coronavirus Disease Outbreak in Call Center, South Korea. [PDF]

Emerg Infect Dis, 2020
Park SY, Kim YM, Yi S, Lee S, Na BJ, Kim CB, Kim JI, Kim HS, Kim YB, Park Y, Huh IS, Kim HK, Yoon HJ, Jang H, Kim K, Chang Y, Kim I, Lee H, Gwack J, Kim SS, Kim M, Kweon S, Choe YJ, Park O, Park YJ, Jeong EK.   +25 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

How a Novel Approach of Allergy Call Center Improved the Management of the Anti-COVID Vaccination Campaign in Piedmont: Italy. [PDF]

J Epidemiol Glob Health
Badiu I, Nicola S, Rashidy N, Della Mura S, Tarrini D, Bernardi V, Gallicchio M, Ridolfi I, Saracco E, Montabone E, Mazzola M, Lo Sardo L, Geronazzo G, Comola L, Apricena A, Vitali I, Quinternetto A, Alessi L, Meli F, Boem M, Teocchi M, Schinocca S, Azzolina MCR, Corradi F, Negrini S, Rolla G, Borrelli R, Brussino L.   +27 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

The association of different types of stress, and stress accumulation with low back pain in call-center workers - a cross-sectional observational study. [PDF]

BMC Musculoskelet Disord
Brenner-Fliesser M, Houtenbos S, Ewerton M, Bontrup C, Visscher R, Taylor WR, Zemp R, Wippert PM.   +7 more
europepmc   +1 more source

Creating a Radiology Call Center Hotline and "HOT" Sites: Centralizing Radiology Questions and Cohorting Out-patient Care During the COVID-19 Pandemic. [PDF]

Curr Probl Diagn Radiol, 2021
Jang B, Facchini D, Staib L, Fernandez A, Pye S, Goodman RT, Granucci C, Nardecchia N, Pahade JK.   +8 more
europepmc   +1 more source