Results 81 to 90 of about 1,814,341 (282)

Florian Bieber: The Rise of Authoritarianism in the Western Balkans

open access: yesComparative Southeast European Studies, 2021
Mujanović Jasmin
doaj   +1 more source

States and Social Complexity: The Indus Valley (Harappan) Civilisation [PDF]

open access: yes, 2012
This article explores 'statehood' and argues Indus Valley (Harappan) Civilisation was not a state like contemporary Sumer and Egypt were, despite being equally complex - hence calling for revision of the unilineal anthropological model culminating in the
Riisfeldt, Thomas David
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Intersecting Pathways: Exploring the Mediating Role of Calling and Affective Commitment Through Self-Compassion in Job Satisfaction Enhancement

open access: yesAdministrative Sciences
This study aims to reveal the significance of self-compassion, job satisfaction, calling, and affective commitment in the context of safety workers. The sample of the study consists of security personnel working in the public sector.
Hasan Huseyin Uzunbacak   +4 more
doaj   +1 more source

Shared Responsibilities for Nuclear Disarmament: A Global Debate [PDF]

open access: yes, 2010
Presents Sagan's 2009 paper calling for rethinking the balance of responsibilities and the relationship between articles in the Nuclear Non-Proliferation Treaty with seven response papers by international scholars about how to pursue nuclear ...
Achilles Zaluar   +7 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Expanding Our Boundaries With Information Literacy

open access: yes, 2002
Years ago I had a calling to a special ministry, but I didn\u27t think of it that way. At the time it seemed more a desire, whereas callings had to do with going into overseas missionary work or into a full time Christian ministry.
Breivik, Patricia Senn
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Calling and conscience: Paul as an example

open access: yesVerbum et Ecclesia
Paul’s calling presents a conundrum to which many have proposed varied solutions. Not trying to solve the conundrum in toto, this study investigates the existential dynamics of Paul’s calling as narrated to the Galatians within the context of their ...
Gert J. Malan
doaj   +1 more source

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