Results 111 to 120 of about 4,438 (333)

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira   +12 more
wiley   +1 more source

The incidence of scarring on the dorsum of the hand [PDF]

open access: yes, 2013
When undertaking image comparison of the hand between accused and perpetrator, it is not unusual for scars to be identified on the back of the hand.
A Conan Doyle   +34 more
core   +4 more sources

Ring Formation in Sesquiterpene Synthesis: Biomimetic vs. Non‐Biomimetic Strategies

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A short review of cyclase enzyme‐mediated ring formation in sesquiterpene biosynthesis is presented as a prelude to six case studies examining the merits and demerits of biomimetic vs. non‐biomimetic strategies for carbocyclisation in the total synthesis of this iconic natural product class.
Bohan Lin, Chen Dai, Alan C. Spivey
wiley   +1 more source

An Improved Transformation System for Molecular Biology Research in Peach Fruit

open access: yesFuture Postharvest and Food, EarlyView.
Schematic Diagram of Repeated Agrobacterium‐Mediated Transformation. A triple‐stage on‐tree Agrobacterium injection enables gene manipulation in peach with up to 32‐day expression, supporting efficient, nonheritable functional analysis without tissue culture.
Chunhong Li   +7 more
wiley   +1 more source

New genera, species and records of Afrotropical Phaneropterinae (Orthoptera, Tettigoniidae) preserved at the Royal Belgian Institute of Natural Sciences, Bruxelles. [PDF]

open access: yes, 2017
The results of the study of the rich material of Orthoptera Phaneropterinae at the Royal Belgian Institute of Natural Sciences, Bruxelles, are reported. The following new taxa are described: Dithela longicaudata n. sp.
Massa B.
core   +1 more source

Complex presentations of child conduct problems: Validation of a competency‐based model for clinical practice

open access: yesJCPP Advances, EarlyView.
Abstract Background Children with conduct problems often present with a range of complex needs and many factors have the potential to complicate the delivery of evidence‐based interventions for conduct problems. Little, however, is known about how to optimise the delivery of such interventions for complex cases, and there has been a lack of consensus ...
Jessica M. Barker, David J. Hawes
wiley   +1 more source

Psychopathy traits and their link to emotion recognition impairments in conduct disorder

open access: yesJCPP Advances, EarlyView.
Abstract Background Neurocognitive models suggest that callous‐unemotional (CU) traits in youths with conduct disorder (CD) are linked to emotion recognition impairments, particularly in identifying distress emotions like fear and sadness. However, CD may be accompanied by grandiose‐manipulative (GM) and/or impulsive‐irresponsible (II) traits in ...
Gregor Kohls   +9 more
wiley   +1 more source

Sequelae of child maltreatment: Umbrella synthesis of 148 meta‐analyses on the mental health correlates

open access: yesJCPP Advances, EarlyView.
Our umbrella synthesis found strong, often equivalent, associations between child maltreatment and all examined mental health difficulties. Different types of maltreatment appear to have comparably negative effects on mental health. If replicated, these findings may cause us to reconsider conventional wisdom that suggests some forms of CM are less ...
Barry Coughlan   +7 more
wiley   +1 more source

Infant frontal alpha asymmetry predicts social attention and transdiagnostic risk for emotional reactivity

open access: yesJCPP Advances, EarlyView.
Abstract Background Differences in Frontal Alpha Asymmetry (FAA), derived from the electroencephalogram (EEG), have been associated with approach‐withdrawal behavior, although inconsistently. The current study examined how early patterns of FAA during the first 2 years of life relate to various socioemotional characteristics (at 2 years) and ultimately
Viviane Valdes   +3 more
wiley   +1 more source

Promoting Fun or Competition? Testing Interventions on Ludic and Agonistic Work Design

open access: yesJournal of Organizational Behavior, EarlyView.
ABSTRACT Research highlights the benefits of play‐at‐work, yet little is known about training employees to self‐initiate it. We tested two programs to train employees on designing work with elements of fun (ludic work design [LWD]) or competition (agonistic work design [AWD]).
Jan E. Walsken   +2 more
wiley   +1 more source

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