Results 41 to 50 of about 2,340 (280)

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

open access: yesAdvanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan   +10 more
wiley   +1 more source

A hypothesis concerning callose [PDF]

open access: yesPlant Signaling & Behavior, 2018
Background Concept: Certain proteins and the glucose monomer have spacing of their carbonyl oxygen atoms that match the spacing of the oxygen atoms of hexagonal ice. This opens the possibility that a sequence of linked glucose residues may have a sequence of equally spaced carbonyl oxygen atoms.
openaire   +2 more sources

Debridement of painful forefoot plantar callosities in rheumatoid arthritis: the CARROT randomised controlled trial

open access: yes, 2013
The objective of this study was to evaluate the long-term benefits of sharp scalpel debridement of painful forefoot plantar callosities in rheumatoid arthritis (RA).
Siddle, HJ   +6 more
core   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

open access: yesAdvanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan   +6 more
wiley   +1 more source

Crossed-leg callosities

open access: yesActa Dermato-Venereologica, 1985
We report five patients in whom localised callosities were found on the dorsum of the feet. This was bilateral in four cases and was due to repetitive minor trauma associated with the sitting posture adopted by the patients. Three of the patients also had psoriasis vulgaris which was clinically dissimilar to the lesions we describe.
N H, Cox, A Y, Finlay
openaire   +2 more sources

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

open access: yesAdvanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song   +9 more
wiley   +1 more source

Forefoot plantar pressures in rheumatoid arthritis [PDF]

open access: yes, 2004
We sought to investigate the magnitude and duration of peak forefoot plantar pressures in rheumatoid arthritis. The spatial and temporal characteristics of forefoot plantar pressures were measured in 25 patients with a positive diagnosis of rheumatoid ...
Otter, Simon, Young, A.K., Bowen, C.J.
core  

The impact of rheumatoid arthritis on foot function in the early stages of disease: a clinical case series [PDF]

open access: yes, 2006
BACKGROUND Foot involvement occurs early in rheumatoid arthritis but the extent to which this impacts on the structure and function leading to impairment and foot related disability is unknown. The purpose of this study was to compare clinical disease
Helliwell, Philip S.   +15 more
core   +2 more sources

Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice

open access: yesAdvanced Science, EarlyView.
Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang   +12 more
wiley   +1 more source

Musculoskeletal, hearing and skin problems related to playing the instrument

open access: yesMedycyna Pracy, 2018
Background Physical demands, exposure to noise and intense contact of skin with musical instruments – inevitable in musicians’ job – influence the development of musculoskeletal, hearing and skin problems.
Aleksandra Jacukowicz, Agata Wężyk
doaj   +1 more source

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