Results 171 to 180 of about 65,053 (315)

Coupling of both a transactivation module and a double‐stranded DNA‐binding domain boosts Cas12i3 variant‐based cytosine and adenine editing in plants

Journal of Integrative Plant Biology, EarlyView.
Fusions of a transactivation module and a double‐stranded DNA‐binding domain produced effective Cas12i3 variant‐based cytosine and adenine base editors, with improved C‐to‐T and A‐to‐G base editing efficiency and expanded editing window. Generated herbicide‐resistant rice germplasm by using these base editors demonstrates their potential for precise ...
Chen Zhang, Jingying Li, Yucai Li, Lei Yan, Christina Seok Yien Yong, Shaoya Li, Yubing He, Lanqin Xia   +7 more
wiley   +1 more source

Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review). [PDF]

Int J Mol Med
Chen S, Cui X.
europepmc   +1 more source

The Last Line

Critical Quarterly, EarlyView.
Beci Carver
wiley   +1 more source

Enhanced exonuclease–Cas9 systems promote multiple nucleotide deletions with higher efficiency and broader targeting scope in plants

Journal of Integrative Plant Biology, EarlyView.
Cas9 preferentially generates small indels. By tethering an exonuclease and a DNA‐binding domain (DBD) to Cas9, the Exo‐DBD‐Cas9 system efficiently promotes multiple nucleotide deletions. These expanded deletions enable effective disruption of miRNA‐mediated regulation and relieve translational repression through targeted editing of 3′ untranslated ...
Rui Zhang, Xu Tang, Yao He, Wei Wang, Qiurong Ren, Yiping Qi, Yong Zhang   +6 more
wiley   +1 more source

Modular control of orchid beauty: co-expression networks orchestrate organ development and evolution in Phalaenopsis flower. [PDF]

Plant Mol Biol
Lucibelli F, Carfora A, Varone M, Volpe G, Di Lillo P, Mazzucchiello SM, Saccone G, Salvemini M, Aceto S.   +8 more
europepmc   +1 more source

Optimizations of Cas12a‐ and Cas12i‐based adenine base editors for efficient precision editing in the plant genome

Journal of Integrative Plant Biology, EarlyView.
A strategy coupling high‐activity nucleases with dimeric TadA‐8e optimizes plant Cas12‐based adenine base editors, boosts editing efficiency, and provides precise editors for crop breeding and genomics research.
Xiaoshuang Liu, Shan Jin, Zhi Xiao, Chong Ma, Qing Wang, Huanhuan Wang, Ruohan Zhou, Dongfang Gu, Rongfang Xu, Ruiying Qin, Juan Li, Pengcheng Wei   +11 more
wiley   +1 more source

Deer antler polypeptides promote osteogenesis for fracture healing via activating neurosensory PGE2/EP4/p-CREB axis. [PDF]

J Orthop Translat
He Y, Xi J, Dai H, Fang L, Yu Y, Ying Y, Li J, Fu D, Xia C.   +8 more
europepmc   +1 more source

The multidimensional regulation roles and mechanisms of calcium in fruit quality

Journal of Integrative Plant Biology, EarlyView.
This review explores how calcium signaling molecule integrates plant hormones, environmental cues, and developmental signals to influence external fruit traits, internal nutritional properties, and physiological disorders. ABSTRACT Calcium (Ca2+), a dual‐functional mineral that serves both as an essential structural factor and a signaling molecule ...
Fei Jiang, Siyang Gao, Mengdi Li, Zeqi Zhao, Chengwei Yang, Ji‐Hong Liu, Chunlong Li   +6 more
wiley   +1 more source

A novel non-invasive approach monitoring skeletal stem cell function through ¹⁸F-Pentixafor PET-CT. [PDF]

J Orthop Translat
Li Z, Zhang D, Adili D, Han J, Xie Z, Xu Q, Tian L, Wang G, Wang G, Wang P, Greenblatt MB, Su X.   +11 more
europepmc   +1 more source

De novo stolon organogenesis in potato leaf callus elicited by Agrobacterium tumefaciens stimulus

Journal of Integrative Plant Biology, EarlyView.
Agrobacterium tumefaciens triggers stolon regeneration from potato leaf callus independent of T‐DNA insertion, suggesting a strategy to reprogram callus identity and expand the potential of tissue regeneration. ABSTRACT Plant cells can undergo cellular reprogramming, enabling pluripotent callus formation from excised leaves.
Seung Yong Shin, Su‐Jin Park, Ji‐Sun Park, Ki‐Beom Moon, Jae Sun Moon, Hye Sun Cho, Hyun‐Soon Kim, Hyo‐Jun Lee   +7 more
wiley   +1 more source