Results 171 to 180 of about 14,450 (206)
Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing
Advanced Science, Volume 13, Issue 50, 7 September 2026.A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo +11 more
wiley +1 more source
Advanced Science, Volume 13, Issue 53, 24 September 2026.A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang +12 more
wiley +1 more source
Agrosystems, Geosciences &Environment, Volume 9, Issue 3, September 2026.Abstract Global agricultural systems are increasingly threatened by abiotic and biotic stresses, including drought, heat, salinity, flooding, pathogens, insect pests, and weeds, all of which substantially reduce crop productivity and yield stability.
Werkissa Yali
wiley +1 more source
Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
BMEMat, Volume 4, Issue 3, September 2026.The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
Plantar Angioleiomyoma Masquerading as a Hyperkeratotic Lesion: A Case Report
Clinical Case Reports, Volume 14, Issue 9, September 2026.ABSTRACT Plantar angioleiomyoma may mimic a refractory hyperkeratotic lesion such as a corn. Progressive enlargement, persistent weight‐bearing pain, and failure of keratolytic therapy should prompt further evaluation. Doppler ultrasonography can help identify a deep vascular tumor and guide definitive excision, and histopathological examination ...
Jiandi Wang +3 more
wiley +1 more source
Global Epidemiology of Diabetic Foot: A Systematic Review and Meta‐Analysis
Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.ABSTRACT Introduction Diabetic foot (DF) disease, including ulcerations, amputations, and infections, represents a major cause of morbidity and mortality in individuals with diabetes mellitus (DM). Despite their substantial clinical, social, and economic burden, robust global epidemiological estimates remain limited due to fragmented evidence and ...
Massimo Carollo +8 more
wiley +1 more source
Equine Veterinary Journal, Volume 58, Issue 5, Page 1150-1168, September 2026.Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska +6 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 9, September 2026.Aronia melanocarpa puree (2% and 6%) was incorporated into yogurt with or without Lactobacillus acidophilus DSM 20079. The treatments affected acidification kinetics and textural properties, resulting in reduced hardness and increased water‐holding capacity. Aronia and probiotic supplementation enhanced antioxidant activity, total phenolic content, and
Çiğdem Konak Göktepe +5 more
wiley +1 more source
Natural Product‐Derived Vesicles in Nanotherapeutics
Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley +1 more source
Addressing Overlooked Variables in Preclinical Fracture Repair Research for Improved Translation
Journal of Orthopaedic Research, Volume 44, Issue 9, September 2026.ABSTRACT In preclinical research focused on bone fracture repair, a significant gap exists in understanding and incorporating key variables that influence homeostasis and pathophysiological processes. Factors such as immune system responses, sex differences, pain and innervation, and microbiota are often overlooked.
Christina Capobianco +6 more
wiley +1 more source