Results 61 to 70 of about 632,938 (299)

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Bedside Calculation of Energy Expenditure Does Not Guarantee Adequate Caloric Prescription in Long-Term Mechanically Ventilated Critically Ill Patients: A Quality Control Study

The Scientific World Journal, 2012
Nutrition is essential in critically ill patients, but translating caloric prescriptions into adequate caloric intake remains challenging. Caloric prescriptions (P), effective intake (I), and caloric needs (N), calculated with modified Harris-Benedict ...
E. De Waele, Herbert Spapen, P. M. Honoré, Sabrina Mattens, Thomas Rose, Luc Huyghens   +5 more
doaj   +1 more source

Caloric and protein intake in different periods of hospitalization of patients undergoing hematopoietic stem cell transplantation

Hematology, Transfusion and Cell Therapy, 2018
Objective: To evaluate the nutritional status and caloric and protein intake during the hospitalization of patients undergoing hematopoietic stem cell transplantation. Methods: A retrospective study was performed based on clinical and nutritional data of
Rhayssa Silveira Garios, Patrícia Morais de Oliveira, Aline Silva de Aguiar, Sheila Cristina Potente Dutra Luquetti   +3 more
doaj   +1 more source

Hypothalamic melanin-concentrating hormone neurons integrate food-motivated appetitive and consummatory processes in rats

Nature Communications, 2023
Food intake is determined by learned appetitive responses and physiological “appetition” signals after eating begins. Here, authors show melanin-concentrating hormone (MCH)-producing neurons integrate these processes to promote caloric intake.
Keshav S. Subramanian, Logan Tierno Lauer, Anna M. R. Hayes, Léa Décarie-Spain, Kara McBurnett, Anna C. Nourbash, Kristen N. Donohue, Alicia E. Kao, Alexander G. Bashaw, Denis Burdakov, Emily E. Noble, Lindsey A. Schier, Scott E. Kanoski   +12 more
doaj   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Nutritional strategies for noninvasively ventilated critically ill patients: results from the NUTRINIV retrospective study

BMC Nutrition
Background The ideal nutritional strategy for patients on noninvasive ventilation (NIV) remains uncertain. This study assessed the nutritional management of intensive care unit (ICU) patients undergoing NIV, evaluating discrepancies between actual intake
Francesca Moretto, Teresa Esposito, Federico Verdina, Martina Fracazzini, Luigi Bertali, Marialuisa Donnarumma, Arianna Lucia Magli, Fabio Minelli, Marta Zuliani, Bianca Barone, Lorenza Scotti, Sergio Riso, Michele Umbrello, Stefania Guido, Federico Prato, Gianmaria Cammarota, Rosanna Vaschetto   +16 more
doaj   +1 more source

Reducing Caloric Intake Prevents Ischemic Injury and Myocardial Dysfunction and Affects Anesthetic Cardioprotection in Type 2 Diabetic Rats

Journal of Diabetes Research, 2017
Background. Type 2 diabetes mellitus (T2DM) increases the risk of myocardial ischemia, followed by increased perioperative risk of cardiovascular morbidity.
Charissa E. van den Brom, Christa Boer, Rob F. P. van den Akker, Stephan A. Loer, R. Arthur Bouwman   +4 more
doaj   +1 more source

Elevated liquid sucrose intake increased caloric intake in mice.

, 2014
Sugar, liquid and food intake was analyzed (A). Total caloric, liquid and food caloric intake was determined (B).
Barbara Ernst (596245), Gyöngyi Bárdos (514813), Yvonne Ritze (514812), Jan G. D’Haese (596244), Martin Thurnheer (596246), Stephan C. Bischoff (452478), Bernd Schultes (69013)   +6 more
core   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Within-week and within-year patterns in self-monitoring of dietary intake in adults with obesity participating in a behavioral weight loss program

Health Psychology and Behavioral Medicine
Introduction: Seasonal and within-week variation has been documented in relation to body weight change and self-weighing; however, less is known regarding how patterns of self-monitoring dietary intake vary over time.Methods: The current study conducted ...
Kathryn M. Ross, Taylor N. Swanson, Kelsey M. Arroyo, Armaan Shetty, Meena N. Shankar, Rebecca A. Krukowski   +5 more
doaj   +1 more source