Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá +4 more
wiley +1 more source
Effects of feeding a <i>Bacillus</i>-based direct-fed microbial during a 60-day receiving program on performance and physiological responses of feeder cattle. [PDF]
Limede AC +7 more
europepmc +1 more source
The most threatened plants receive the least scientific attention
Plants sustain all life, providing the energetic and structural basis of ecosystems, but they face a growing risk of extinction. Reversing this decline requires an understanding of how scientific knowledge is distributed among species, and identification of the biases and gaps that hinder effective responses to the threats they face. However, we reveal
Renon S. Andrade +3 more
wiley +1 more source
The interaction between grass species and climatic season shapes the population dynamics of the cattle tick, Rhipicephalus microplus. This information highlights the potential of forage species to influence off‐host tick dynamics. Additionally, minimum temperature and minimum relative humidity were the most influential microclimatic predictors of ...
Valesca Henrique Lima +8 more
wiley +1 more source
Enhancing immune protection in dairy cattle: role of <i>Escherichia coli</i> Nissle 1917 in boosting the efficacy of a <i>Mycoplasma bovis</i>-BoAHV-1 combined vaccine. [PDF]
Zhang S, Liu G, Chen J, Guo A, Chen Y.
europepmc +1 more source
Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
Virulence profiling and biofilm-forming capacity of different <i>E. coli</i> pathotypes and phylogroups isolated from calf diarrhoea. [PDF]
Karahutová L +2 more
europepmc +1 more source
Identification of gut microbiota features of diarrheic calves using the full-length 16S rRNA gene amplicon sequencing and machine learning. [PDF]
Hawkins J +9 more
europepmc +1 more source
Molecular Investigation of <i>Eimeria</i> spp. Infection in Weaned Dairy Calves in Thessaly, Greece, and Associated Risk Factors. [PDF]
Arsenopoulos KV +2 more
europepmc +1 more source

