Results 171 to 180 of about 3,174,638 (320)

Repurposing of the Macrolide Antibiotic Clarithromycin for the Prevention of Lung Cancer. [PDF]

Mol Cancer Ther
Deng S, Hussain T, Bartelli TF, Sebastian MM, Zarghooni M, Velasco WV, Somerville B, Phan L, Savage MI, Song Y, Clifford JL, Kadara H, McAllister F, Brown PH, Moghaddam SJ, Aldaz CM.   +15 more
europepmc   +1 more source

The National Wildlife System Improvement Act of 1997: Defining the National Wildlife Refuge System for The Twenty-First Century [PDF]

, 2000
Tredennick, Cam
core   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

Advanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao, Jiakang Shao, Quanzhi Li, Yizhou Tan, Liangliang Huang, Xiaorong Xu, Ji Qi, Julin Xiao, Wenwen Li, Zhong Wen, Le Wang, Xu Liu, Qing Yang, Ying Gu   +13 more
wiley   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

Advanced Science, EarlyView.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen, Zhihang Xu, Yiping Zou, Zhenlai Jiang, Yecheng Li, Taochen He, Hanlin Yin, Jiali Li, Yanfei An, Jiande Han, Yuqi Xie, Wei Gan, Yaolin Xu, Wenquan Wang, Junyi He, Haibo Wang, Wenchuan Wu, Zhenyu Ye, Wenhui Lou, Jihui Hao, Liang Liu, Jun Yu, Ning Pu   +22 more
wiley   +1 more source

Complementary and alternative medicine use and pain characteristics in older Vietnamese adults with chronic pain: A cross-sectional study. [PDF]

Belitung Nurs J
Trieu NTT, Hoai NTY, Thuy PT, Dung PTA, Ninh DT.   +4 more
europepmc   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Patient-reported outcomes regarding the use of complementary and alternative medicine (CAM) in BCR::ABL1-negative myeloproliferative neoplasias. [PDF]

J Cancer Res Clin Oncol
Crodel CC, Kohnle C, Radsak MP, Nückel H, Jilg S, Hochhaus A, Heidel FH, Hübner J.   +7 more
europepmc   +1 more source

Visualizing Strain‐Coupled Cryogenic Phase Transitions and Defect Dynamics in Perovskite Quantum Dots Using In Situ STEM

Advanced Science, EarlyView.
Cryogenic cooling induces an orthorhombic‐to‐monoclinic phase transition in CsPbBr3 quantum dots, accompanied by pronounced strain localization at surfaces and interfaces. Multimodal in situ STEM directly visualize reversible defect healing during moderate cryogenic treatment and irreversible degradation upon prolonged exposure, revealing the intrinsic
Xinjuan Li, Zhao Jiang, Si Chen, Yi Tang, Bofeng Xue, Tianhao Wu, Yang Lu, Xavier Moya, Akshay Rao, Zhongzheng Yu, Caterina Ducati   +10 more
wiley   +1 more source

Integrated BSI bacteria identifier-on-chip using approximate k-mer matching. [PDF]

Sci Rep
Garzón E, Galindo V, Harary Y, Teman A, Yavits L.   +4 more
europepmc   +1 more source