Results 41 to 50 of about 426,170 (291)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Sanatsal cam olarak kullanım için cam renklendirme ve uygulaması [PDF]

, 2018
Bu çalışmada, Anadolu Üniversitesi, Cam Bölümü imkanlarıyla saydam renkli cam üretmek için denemeler yapılmıştır. Bu denemelerde, seramik krozelerde cam ergitme işlemleri gerçekleştirilmiştir ve ham madde olarak soda-kireç-silika esaslı cam (Glasma 705 ...

core   +2 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Design of cam-linkage combined mechanism based on Fourier series

Shipin yu jixie
ObjectiveTo enhance the motion smoothness and reliability of cam-linkage combined mechanisms under high-speed operating conditions and to investigate a cam profile design method based on Fourier series.MethodsThis study derives the motion law expression ...
TAN Rongdeng, YANG Hongfei, LI Wenyuan, HE Bing, SHA Yulong, ZHANG Zijun, PENG Zijie   +6 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Arkeoloji ve arkeometrinin çağdaş cam sanatına yansımaları [PDF]

, 2021
Arkeoloji bilimi, geçmişte insan hayatının bir parçası olan malzemelerin ortaya çıkışı, üretim yerleri, üretim yöntemleri ve kullanım alanları ve daha birçok bilinmeze ışık tutmaktadır. Arkeolojik çalışmaların başlangıcı çok eski zamanlara dayalı olsa da

core   +2 more sources

Uma metodologia para integração CAD/CAPP/CAM voltada para manufatura remota de peças rotacionais baseada na internet [PDF]

, 2005
Tese [doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia MecânicaEsta tese de doutorado apresenta uma metodologia para integração CAD/CAPP/CAM voltada para manufatura remota de peças ...
Alvares, Alberto Jose
core  

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Four Unrecorded Aspergillus Species from the Rhizosphere Soil in South Korea

Mycobiology, 2021
The genus Aspergillus is commonly isolated from various marine and terrestrial environments; however, only a few species have been studied in rhizosphere soil.
Jun Won Lee, Sung Hyun Kim, Young-Hyun You, Young Woon Lim, Myung Soo Park   +4 more
doaj   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source