Results 141 to 150 of about 6,035,777 (295)
ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models
Advanced Healthcare Materials, EarlyView.A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm +12 morewiley +1 more sourcePrenatal Volume in the Bilateral Superior Temporal Gyrus Associates With Children's Expressive Vocabulary at 24-36 Months. [PDF]
Dev SciWerwach A, Tsompanidis A, Villa L, Tait R, Suckling J, Austin T, Hampton S, Allison C, Holt R, Baron-Cohen S, Schaadt G. +10 moreeuropepmc +1 more sourceDevelopment of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System
Advanced Healthcare Materials, EarlyView.ABSTRACT
The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith +7 morewiley +1 more sourcePublisher Correction: Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome. [PDF]
Nat CommunBalmus G, Larrieu D, Barros AC, Collins C, Abrudan M, Demir M, Geisler NJ, Lelliott CJ, White JK, Karp NA, Atkinson J, Kirton A, Jacobsen M, Clift D, Rodriguez R, Sanger Mouse Genetics Project, Adams DJ, Jackson SP. +17 moreeuropepmc +1 more sourceExtracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury
Advanced Healthcare Materials, EarlyView.This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney +13 morewiley +1 more sourceAuthor Correction: Ocean heat forced West Antarctic Ice Sheet retreat after the Last Glacial Maximum. [PDF]
Nat CommunMawbey EM, Smith JA, Hillenbrand CD, Hendry KR, McClymont EL, Greaves MJ, Klages JP, Kuhn G, Radionovskaya S, Spencer-Jones CL, Larter RD, Wellner JS, Dutrieux P. +12 moreeuropepmc +1 more sourceAirborne 1O2 Delivery via a Superhydrophobic Dressing as a Pathway to Next‐Generation Wound Therapies, an in Vivo Murine Burn Model Study
Advanced Healthcare Materials, EarlyView.Schematic illustration of the SH bandage placed on an infected burn wound and its role in wound healing. A superhydrophobic PDMS membrane coated with the PS verteporfin is placed over the wound area and illuminated with a red laser at 690 nm, generating airborne 1O2 above the tissue.Fernanda Viana Cabral, QianFeng Xu, Natalie Eidenschink, Pareesha Haresh, Alessandra Nara de Souza Rastelli, Jeremy Goverman, Alexander Greer, Alan M. Lyons, Tayyaba Hasan +8 morewiley +1 more sourceCorrection: Leveraging paired serology to estimate the incidence of typhoidal Salmonella infection in the STRATAA study. [PDF]
PLoS Negl Trop DisWalker J, Russell P, Kermack L, Van TT, Thieu Nga TV, Mylona E, Camara S, Kim YC, Shrestha S, Gehlhaar A, Scott JB, Khanam F, Shakya M, Thindwa D, Gordon MA, Basnyat B, Clemens JD, Qadri F, Heyderman RS, Dolecek C, Tonks S, Darton TC, Pollard AJ, Baker S, Meiring JE, Voysey M, Pitzer VE, and the STRATAA Study Group. +27 moreeuropepmc +1 more source