Results 71 to 80 of about 2,200 (159)

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4512-4531, August 2026.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, Volume 13, Issue 37, 3 July 2026.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Management software for pedigree and production of New World Camelids: Pacokipu and Llamakipu

Revista de Investigaciones Veterinarias del Perú, 2021
Genealogical and productive records are the most important pillars within genetic and genomic improvement programs, where the diversity of data that can be collected must be systematized and related, to carry out an adequate statistical analysis considering all the factors that influence the variables.
Cruz, Alan, Gutiérrez, Gustavo, Burgos, Alonso, Morante, Renzo, Wurzinger, María, Gutiérrez, Juan Pablo   +5 more
openaire   +1 more source

New evidence of the sabertooth cat Smilodon (Carnivora: Machairodontinae) in the late Pleistocene of southern Chilean Patagonia Nueva evidencia del gato dientes de sable Smilodon (Carnivora: Machairodontinae) en el Pleistoceno tardío de Patagonia meridional chilena

Revista Chilena de Historia Natural, 2010
Southern Patagonia is rich in late Pleistocene mammals, especially herbivores such as Camelids, Equids and Xenarthrans. Carnivores, on the other hand, are not commonly found in the paleontological record.
ALFREDO PRIETO, RAFAEL LABARCA, VÍCTOR SIERPE   +2 more
doaj  

New World camelids and Bovine Virus Diarrhea Virus (BVDV) infection in Switzerland [PDF]

Schweizer Archiv für Tierheilkunde, 2012
Hilbe, Monika, Kaufmann, Ch, Zlinszky, Katalin, Zanolari, P, Ehrensperger, Felix   +4 more
openaire   +3 more sources

Molecular and morphological characteristics of <i>Trichuris tenuis</i> from South American Camelids bred in Europe. [PDF]

Front Vet Sci
Rejnková S, Daněk O, Máca O, Modrý D, Hrabětová V, Veneziano V, Castaldo E, Oros M, Patoka J, Čadková Z, Jankovská I, Neradilová S, Kotrba R, Ptáček M, Langrová I.   +14 more
europepmc   +1 more source

Serological investigation on Sarcocystis spp. infection and associated risk factors in South American camelids in Italy. [PDF]

Parasitol Res
Castaldo E, Moré G, Schares G, Buono F, Scarcelli S, Sgroi G, Humak F, Basso W, Veneziano V.   +8 more
europepmc   +1 more source

Biochemical and blood gas parameters in llamas (Lama glama) raised at moderate altitude: preliminary data from a subtropical environment. [PDF]

Trop Anim Health Prod
Marques ALR, Marangoni M, Mamgue VE, Braz PH.   +3 more
europepmc   +1 more source

A dual-center retrospective evaluation of 204 blood or plasma transfusions in 169 camelids. [PDF]

J Vet Intern Med
Mullins CR, Oman RE, Gebhardt JT, Reppert EJ.   +3 more
europepmc   +1 more source