Results 61 to 70 of about 20,119,452 (193)

Environment Matters at the World Bank : Annual Review 2005 [PDF]

, 2005
In line with one of the major themes in the Bank's Environment Strategy, this 2005 annual review is devoted to the theme of environmental health. Viewpoint articles in this edition reflect several external
World Bank
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Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

A World Bank Retrospective

, 2023
As the largest external financier of education in low- and middle-income countries, the World Bank is committed to ensuring that all children around the world have free, inclusive, equitable, and quality education
World Bank
core   +1 more source

The Camel Adaptive Immune Receptors Repertoire as a Singular Example of Structural and Functional Genomics

Frontiers in Genetics, 2019
The adaptive immune receptors repertoire is highly plastic, with its ability to produce antigen-binding molecules and select those with high affinity for their antigen.
Salvatrice Ciccarese, Pamela A. Burger, Elena Ciani, Vito Castelli, Giovanna Linguiti, Martin Plasil, Martin Plasil, Serafina Massari, Petr Horin, Petr Horin, Rachele Antonacci   +10 more
doaj   +1 more source

The Late Agricultural Development of Central Arabian Oases—Archaeobotanical and Archaeozoological Studies of the al‐Kharj Oasis

Arabian Archaeology and Epigraphy, EarlyView.
ABSTRACT While oasis settlements emerged during the Bronze Age in Eastern and Northern Arabia, the settlement process in Central Arabia was different. Excavations at al‐Yamāma—main ancient settlement of the al‐Kharj oasis (Riyadh Province, KSA)—suggest that the latter did not emerge before the second half of the first millennium BCE.
Elora Chambraud, Hervé Monchot, Vladimir Dabrowski, Charlène Bouchaud, Jérémie Schiettecatte   +4 more
wiley   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Timing the Sacred: A Multi‐Step Chronological Framework for the Llullaillaco Inca Burial

Archaeometry, EarlyView.
ABSTRACT Absolute radiocarbon dating offers high precision, but its application to historical contexts, such as the Inca civilization, requires a rigorous methodological approach. This research examines methods to enhance chronological accuracy through a case study of artifacts from the Llullaillaco Capacocha sacrifice.
Dominika Sieczkowska‐Jacyna, Gabriela Recagno Browning, Mario Bernaski, Fernanda Zigaran, Maksymilian Jędrzejowski, Jacek Pawlyta, Andrzej Rakowski, Johan Reinhard, Sturt W. Manning, Dagmara Socha   +9 more
wiley   +1 more source

Application of New World Camelidae microsatellite primers for amplification of polymorphic loci in Old World camelids

Animal Genetics, 2000
Twenty new world camelidae primer pairs were selected for cross-species amplification of loci in the old world camelids, the dromedary (Camelus dromedarius) and the bacterian (camelus bactrianus). A panel of DNA samples from 34 unrelated dromedaries (Kenya) and from 34 unrelated bactrians (32 domestic bactrians and two wild bactrians, China) were ...
D.N, Mburu, H, Jianlin, J, Ochieng, B, Kaufmann, J E O, Rege, O, Hanotte   +5 more
openaire   +3 more sources

Integrated Engineering of CAR‐T Cells for Solid Tumours

Cell Proliferation, EarlyView.
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang, Tan Li, Ping He, Zhijie Zhao, Shenglong Li, Liming Wang   +5 more
wiley   +1 more source

The Digestive System of New World Camelids - Common Digestive Diseases of Llamas [PDF]

, 1988
Llamas (Lama glama) belong to a group of animals called South American or New World Camelids, which also includes the Guanaco (Lama guanicoe) , the Vicuna (Lama vicugna) and the Alpaca (Lama pacos). They are originally from South America, residing in the
Esteban, L., Thompson, J.
core